摘要
目的:探讨阿奇霉素联合转移因子口服溶液对小儿肺炎支原体肺炎的疗效。方法:肺炎支原体肺炎患儿100例随机分为观察组和对照组各50例,观察组采用阿奇霉素联合转移因子口服溶液治疗,对照组单用阿奇霉素。疗程2用结束后观察疗效,随访2月观察有无复发。结果:观察组发热、咳嗽、肺部体征消失和X线胸片恢复时间和对照组比较差异均有统计学意义(P<0.05);两组间治愈率差异有统计学意义(P<0.05);观察组无复发,对照组3例(6%)复发。结论:阿奇霉素联合转移因子口服溶液治疗小儿肺炎支原体肺炎疗程短,治愈率高,复发率低,提示联合用药具有明显的优越性。
Objective ：To investigate the therapeutic efficacy of azithromycin with transfer factor oral solution in treatment of children with myeoplasma pneumoniae pneumonia （MPP）. Methods： 100 eases of children with MPP were randomly divided into two groups with 50 cases each： the observation group received the combined therapy of azithromyein with transfer factor oral solution, while the control group received the therapy of azithromyein only, and then comparison was made between the two groups in clinical effects in the end of the course of 2 weeks＇ treatment and follow-up visits were made after 2-month to see whether there was any recrudescence. Results： There was a significant difference between the two groups （ P 〈 0.05 ） in the time of the disappearance of fever, cough and pulmonary signs and of X-ray recovery, and there was also a statistic difference in curative rate （ P 〈 0.05 ）. No ease relapsed in the observation group while 3 cases （6%） in the control group. Conclusions： The combined therapy of azithromyein with transfer factor oral solution has obvious superiority with shorter courses, higher curative rate and lower relapse rate than single azithromycin in treatment of children with MPP.
出处
《儿科药学杂志》
CAS
2008年第2期45-47,共3页
Journal of Pediatric Pharmacy
关键词
肺炎支原体肺炎
免疫调节剂
联合用药
Mycoplasma pneumoniae pneumonia
Immunoregulant
Drug combination
