期刊文献+

个性化医学时代的病理学 被引量:15

原文传递
导出
摘要 过去和现在的病理学主要有3个组成部分即尸检、外检和细胞学。尸检曾在20世纪中叶以前占重要地位,20世纪中后期转向外检和细胞学,病理学的重点从学院式病理(academic pathology)转向临床即外科病理(诊断病理)。病理医师成为临床医师重要的咨询和会诊专家。
作者 刘彤华
出处 《中华病理学杂志》 CAS CSCD 北大核心 2008年第4期217-218,共2页 Chinese Journal of Pathology
  • 相关文献

参考文献16

  • 1Dietel M, Sers C. Personalized medicine and development of targeted therapies : the upcoming challenge for diagnostic molecular pathology. A review. Virchows Arch, 2006, 448 (6) :744-755. 被引量:1
  • 2Watson MA, Perry A, Budhraja V, et al. Gene expression profiling with oligonucleotide microarrays distinguishes World Health Organization grade of oligodendrogliomas. Cancer Res, 2001,61 (5) : 1825-1829. 被引量:1
  • 3Bhattacharjee A, Richards WG, Staunton J, et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci U S A, 2001,98(24) :13790-13795. 被引量:1
  • 4Giordano TJ, Shedden KA, Schwartz DR, et al. Organ-specific molecular classification of primary lung, colon, and ovarian adenocarcinomas using gene expression profiles. Am J Pathol, 2001, 159(4) :1231-1238. 被引量:1
  • 5van't Veer L J, Dai H, van de Vijver MJ, et al. Expression profiling predicts outcome in breast cancer. Breast Cancer Res, 2003,5( 1 ) :57-58. 被引量:1
  • 6曾瑄,梁智勇,武莎斐,周炜洵,高洁,刘彤华.乳腺癌HER2蛋白表达阳性者的基因状态分析[J].中华病理学杂志,2006,35(10):584-588. 被引量:40
  • 7张瑰红,施达仁,梁晓曼,侯景辉,康苏娅,朱卫东,李晓兵,邵云,陈丽荣,周燕.显色原位杂交和免疫组织化学检测乳腺癌HER2/neu基因状况和蛋白表达的对照性研究[J].中华病理学杂志,2006,35(10):580-583. 被引量:29
  • 8Lesko LJ. Personalized medicine: elusive dream or imminent reality? Clin Pharmacol Ther, 2007,81 (6) :807-816. 被引量:1
  • 9Fierz W. Challenge of personalized health care: to what extent is medicine already individualized and what are the future trends? Med Sci Monit, 2004,10(5) :RA111-RA123. 被引量:1
  • 10Ross JS, Ginsburg GS. The integration of molecular diagnostics with therapeutics. Implications for drug development and pathology practice. Am J Clin Pathol, 2003,119( 1 ) :26-36. 被引量:1

二级参考文献36

  • 1曾瑄,赵大春,周炜洵,武莎斐,梁智勇,刘彤华.荧光原位杂交检测乳腺癌HER2基因状态[J].中华病理学杂志,2005,34(11):701-705. 被引量:65
  • 2Jacobs TW,Gown AM,Yaziji H,et al.Comparison of fluorescence in situ hybridization and immunohistochemistry for the evaluation of HER-2/neu in breast cancer.J Clin Oncol,1999,17:1974-1982. 被引量:1
  • 3Zhao J,Wu R,Au A,et al.Determination of HER2 gene amplification by chromogenic in situ hybridization (CISH) in archival breast carcinoma.Mod Pathol,2002,15:657-665. 被引量:1
  • 4Isola J,Tanner M,Forsyth A,et al.Interlaboratory comparison of HER-2 oncogene amplification as detected by chromogenic and fluorescence in situ hybridization.Clin Cancer Res,2004,10:4793-4798. 被引量:1
  • 5Amould L,Denoux Y,MacGrogan G,et al.Agreement between chromogenic in situ hybridisation (CISH) and FISH in the determination of HER2 status in breast cancer.Br J Cancer,2003,88:1587-1591. 被引量:1
  • 6Yaziji H,Goldstein LC,Barry TS,et al.HER-2 testing in breast cancer using parallel tissue-based methods.JAMA,2004,291:1972-1977. 被引量:1
  • 7Press MF,Santer G,Bernstein L,et al.Diagnostic evaluation of HER-2 as a molecular target:an assessment of accuracy and reproducibility of laboratory testing in large,prospective,randomized clinical trials.Clin Cancer Res,2005,11:6598-6607. 被引量:1
  • 8Dolan M,Snover D.Comparison of immunohistochemical and fluorescence in situ hybridization assessment of HER-2 status in routine practice.Am J Clin Pathol,2005,123:766-770. 被引量:1
  • 9Lan C,Liu JM,Liu TW,erb-b2 amplification by fluorescence in situ hybridization in breast cancer specimens read as 2 + in immunohistochemical analysis.Am J Clin Pathol,2005,124:97-102. 被引量:1
  • 10Merola R,Mottolese M,Orlandi G,et al.Analysis of aneusomy level and HER-2 gene copy number and their effect on amplification rate in breast cancer specimens read as 2 + in immunohistochemical analysis.Eur J Cancer,2006,42:1501-1506. 被引量:1

共引文献73

同被引文献172

引证文献15

二级引证文献79

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部