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心尖肥厚型心肌病53例临床分析

Clinical analysis of 53 patients with apical hypertrophic cardiomyopathy
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摘要 目的探讨心尖肥厚型心肌病(AHCM)的临床表现,心电图特点、冠状动脉造影(CAG)结果和长期预后情况。方法对53倒经超声心动图确诊的AHCM患者,进行病史回顾,体格检查、心电图和CAG检查,并通过电话和门诊随访,了解心血管事件发生情况。结果AHCM患者病史不典型,但心电图有特征性变化,表现为胸前导联巨大倒置T波,尤其以V4导联显著,伴有ST段下移,常被误诊为冠心病。30例行CAG者中28例示左冠状动脉明显增粗;3例发现器质性狭窄,并成功置入支架;7例发现心肌桥,均位于左前降支。经0.4~7.5年的随访,仅1例死于癌症。结论AHCM有比较典型的心电图表现,左冠状动脉内径增粗,常并发肌桥和冠心病,远期预后较好。 Objective To explore the clinical manifestations, ECG characteristics,coronary angiography resultsand long--term prognosis of apical hypertrophic cardiomyopthy (AHCM).Method:Fifty--three patients with AH--CM ,confirmed by ultrasound cardiography, were received history review, physical examinations, ECG tests, and/or coronary angiography. Long--term follow--up was conducted by telephone or at outpatients' room to ascertain the incidence of cardiovascular events. Result:The history of AIICM was not typical, but its ECG had characteristic changes, which showed great inverted T wave with ST segment depression at precordial leads, especially at V41cad. It was usually misdiagnosed as coronary heart disease, especially non--Q wave myocardial infarction. Among30 patients undergoing coronary angiography, 28 patients showed large left coronary arteries, while 3 patients hadsignificant stenotic lesion and then received successful stenting. Myocardial bridge was found in 7 patients. Duringthe follow--up period of 0·4-7·5 years, only I patients died of cancer.Conclusion:AHCM has typical ECG changeswith large left coronary arteries and good long-term prognosis, usually coexisting with myocardial bridges and coronary heart disease.
出处 《中外医疗》 2008年第5期21-22,共2页 China & Foreign Medical Treatment
关键词 心肌病 肥大型 心电描记术 冠状动脉造影 预后 Cardiomyopathy, apical hypertrophy Electrocardiography Coronary angiography Prognosis
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