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补肾活血颗粒抗衰老作用研究

Study on Anti-aging Effect of Bushenhuoxue Granules
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摘要 目的观察补肾活血颗粒的抗衰老作用。方法对16月龄SD大鼠连续给予补肾活血颗粒45d,末次给药后取血分离测定超氧化物歧化酶(SOD)和丙二醛(MDA),取胸腺、脾、肾上腺计算脏器系数。结果老年组大鼠的SOD活力明显降低,而MDA含量升高,补肾活血颗粒连续给药可明显升高SOD活力,降低MDA含量,对脏器系数未见明显影响。结论补肾活血颗粒可明显减少脂质过氧化反应,具有抗衰老作用。 Objective To observe the anti-aging effect of Bushenhuoxue Granules. Methods The SD rats aged 10 months were given Bushenhuoxue Granules continuously for 45 d. After the last medication,the blood was taken out and separated to measure SOD and MDA. The organ coefficients of thymus gland, spleen and adrenal gland were determined. Results SOD in the aging group debased obviously and MDA content increased, but had not obvious influence on the organ coefficients. Conclusion Bushenhuoxue Granules can obviously lessen the peroxidized course of lipoids with anti-aging action.
出处 《中国药业》 CAS 2008年第7期14-15,共2页 China Pharmaceuticals
关键词 补肾活血颗粒 超氧化物歧化酶 丙二醛 药效学 Bushenhuoxue Granules SOD MDA pharmacodynamics
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