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甲磺酸帕珠沙星与利巴韦林在氯化钠注射液中的稳定性考察 被引量:2

Stability of Pazufloxacin Mesilate for Injection Mixed with Ribavirin Injection in Chloride Solution
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摘要 目的:考察注射用甲磺酸帕珠沙星与利巴韦林注射液在氯化钠注射液中的配伍稳定性。方法:采用紫外分光光度法测定注射用甲磺酸帕珠沙星与利巴韦林注射液配伍后的含量,观察配伍液的外观变化及pH值。结果:室温条件下8 h内配伍液的外观、pH值及甲磺酸帕珠沙星与利巴韦林含量均无明显变化。结论:注射用甲磺酸帕珠沙星与利巴韦林注射液可以在氯化钠注射液中配伍使用。 Objective: To study the stability of compatibility of Pazufloxacin Mesilate Injection with ribavirin injection in chloride solution. Methods: The contents of Pazufloxacin Mesilate and ribavirin were detected by UVspectrophotometry and the external appearance and pH value were observed after Pazufloxacin Mesilate and ribavirin in chloride solution were mixed for 8 h at the room temperature. Results: The contents, external appearance and pH value of the mixed solution showed no significant changes within 8 h. Conclusions: Pazufloxacin Mesilate Injection mixed with ribavirin injection in sodium chloride solution could be kept stable within 8 h.
出处 《抗感染药学》 2008年第1期30-33,共4页 Anti-infection Pharmacy
关键词 甲磺酸帕珠沙星 利巴韦林 配伍稳定性 紫外分光光度法 pazufloxacin mesilate ribavirin stability of compatibility UV spectrophotometry
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