摘要
目的探讨颈动脉内膜中层厚度(IMT)与中青年阻塞性睡眠呼吸暂停低通气综合症(OSAHS)的关系。方法测定39例中青年OSAHS(其中19例合并高血压)患者清晨7时血压、呼吸暂停低通气指数(AHI)和颈动脉IMT值,并选择年龄、性别、体重指数相匹配的正常人作为对照。结果中重度中青年OSAHS的颈动脉IMT值较正常人和轻度OSAHS显著增加(P<0.01),OSAHS合并高血压较单纯性OSAHS患者的颈动脉显著增加(P<0.01)。结论中青年中重度OSAHS已存在血管形态学改变,合并高血压以后,这一趋势将更明显。
Objective To discuss the association between the carotid intima-media thickness（IMT） and adult obstructive sleep apnea hypoventilation Syndrom（OSAHS）.Methods Blood pressure at 7：00AM,apnea hypoventilation index（AHI）,the lowest arterial oxygen saturation（ LSaO2）,carotid IMT were measured in 39 adult patients with OSAHS.Among them,19 patients had been already got diagnosis of hypertension.Normal people with matched age,sex and body mass index （BMI）were chosen as control group.The differences of carotid IMT were evaluated.Results the carotid IMTs were signifincant increased in the moderate and severe adult OSAHS patients compared with mild patients and normal people（P〈0.01）,and were more significant in the OSAHS patients with hypertension than those with pure OSAHS（P〈0.01）.Conclusion vascular morphologic chang has already been existed in the moderate and severe adult OSAHS patients;the trend of which could be more significant after developing hypertension.
出处
《临床内科杂志》
CAS
2008年第3期183-184,共2页
Journal of Clinical Internal Medicine
