摘要
非水毛细管电泳在效率、分析速度和选择性上比水介质毛细管电泳有优势,同时由于有机溶剂的高挥发性和低表面张力使其适合与质谱联用。本综述涉及溶剂效应对NACE-MS的影响,样品堆积技术及在药物分析和手性分析中的应用。
The advantages of nonaqueous capillary electrophoresis （NACE） over the aqueous mode are efficiency, speed and selectivity. NACE appears to be ideally suited for online coupling with mass spectrometry due to the high volatility and low surface tension of many organic solvents. The present review summarizes the application of online NACE-MS with regard to analysis of drugs and stereoisomer.
出处
《质谱学报》
EI
CAS
CSCD
2008年第2期120-128,共9页
Journal of Chinese Mass Spectrometry Society
基金
国家自然科学基金(20672143,30271608)资助
关键词
非水毛细管电泳
质谱
联用
nonaqueous capillary electrophoresis
mass spectrometry
online coupling
