摘要
用免疫组化ＬＳＡＢ法检测了４２例食管鳞癌中人绒毛膜促性腺激素（ＨＣＧ）的表达。结果发现：淋巴结转移组的阳性表达率为８５．７１％（１８／２１），而非转移组的阳性表达率为５７．１４％（１２／２１），两组之间差异显著（Ｐ＜０．０５）。从Ⅰ级癌到Ⅲ级癌，其阳性率依次为８４．６２％（１１／１３）、７０．５９％（１２／１７）和５８．３３％（７／１２），彼此间差异无显著性（Ｐ＞０．０５）。癌栓中的癌细胞和浸润血管壁的癌细胞呈强阳性表达。提示：ＨＣＧ表达与食管鳞癌的淋巴道、血道转移有关。
With labbelled streptavidin biotin(LSAB) technique,we examined the expression of HCG in the specimens of 42 esophageal squamous carcinomas .The result are as follows:in the metastatic group,the positive rate of HCG was 85.71%(18/21),while in the nonmetastatic group,the positive rate was 57.14% (12/21).There was a significant difference between the two groups (P<0.05).From Grade Ⅰ to Grade Ⅲ carcinomatous tissues,the positive rates of HCG were 84.62%(11/13),70.59%(12/17) and 58.33%(7/12) respectively,there was no significant difference among them (P>0.05).There were strong expression of HCG in the cancerous cells in the carcinomatous emboli and the infiltrated vascular walls.It suggests that there may be a positive correlation between the expression of HCG and the lymph vascular metastasis of esophageal squamous cell carcinoma.
出处
《河南医科大学学报》
1997年第3期47-50,共4页
Journal of Henan Medical University
基金
国家"八五"科技攻关项目
河南省重大科技攻关项目
