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排菌肺结核病人化学疗法前后痰涂片与培养检查结果的观察研究

A study on smear and culture examined for tubercle bacilli before and during chemotherapy among pulmonary tuberculosis
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摘要 本文对323例完成全面监督下短程化疗的肺结核病人治疗前后痰涂片和培养结果进行了分析。治疗前首次痰标本检查,涂片和培养阳性率分别为80.1%和93%(P<0.01),第二个标本检查涂片与培养阳性率分别增加了13.6%和2.8%。即两个痰标本涂片的阳性检出率相当于一次培养的阳性率。痰涂阳培阴病例在化疗第一个月为18.4%,第二个月最高为20.2%,持续至第六个月仍有2.9%的病例。化疗后第二个月痰培养的阴转速度比涂片高出约19%,培养第二个月阴转率达95.2%,而涂片阴转率仅76.1%。本研究建议诊断前或化疗期间除进行涂片检查外,如有条件可进行痰培养检查。 The results of smear and culture examined for tubercle bacilli before chemotherapy and during chemotherapy were observed among 323 patients who completed 6 month short-course regimen under fully supervision. The positive rates of smear and culture examination in the first specimen of sputum before treatment were 80.1% and 93% (P<0.01) respectively. If adding the second sputum specimen, the positive rates of smear and culture were increased to 13.6% and 2.8% respectively, which means the positive rate of two sputum specimen by smear was similar to one specimen by culture. During chemotherapy, smear positive and culture negative rate was 18.4% in the first month treatment, 20.2 in the second month and still 2.9% at the end of 6 month treatment. The sputum conversion rates examined by smear and culture at the end of second month chemotherapy were 76.1% and 95.2% respectively, which means the conversion rate by culture method is 19% higher than by smear at the end of two month chemotherapy. It is recommended that culture examination for tubercle bacilli should be used if possible before treatment and during chemotherapy.
作者 马增启
出处 《中国防痨杂志》 CAS 1997年第3期137-137,共1页 Chinese Journal of Antituberculosis
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  • 1A. Laszlo,V. Handzel. Radiometric diagnosis of mycobacteria[J] 1986,European Journal of Clinical Microbiology(2):152~155 被引量:1

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