摘要
检测脑出血并发多器官功能衰竭（ＭＯＦ）患者外周血Ｔ细胞亚群的变化，发现其值比正常人明显降低，它们分别是ＣＤ＋３４０．６１±４．５３，ＣＤ＋４２８．３６±４．７１，ＣＤ＋８２３．２２±６．７６，影响Ｔ细胞亚群改变的原因主要是由于脑出血引起脑水肿，破坏了儿茶酚胺与多巴胺的分泌，影响了Ｔ细胞的生成与激活；另外，脑出血对呼吸中枢的影响及并发肺部感染致缺氧和二氧化碳潴留也影响Ｔ细胞亚群的生成。
The level of peripheral blood T lymphocyte subpopulations was observed in patients of cerebral hemorrhage (CH) complicated with multiple organ failure (MOF) and in normal controls. the results ahowed that the decrease of blood CD + 3 (40.61±4.53), CD + 4 (28.36±4.71) CD + 8 (23.22±6.76) was of significance in CH with MOF, which suggested that the main reason for the change of T lymphocyte subpopulations may be related to cerebral edema caused by CH that destoried the secrection of catecholamine and dopamine , and that affected the production and stimulation of T lymphocyte. In addition, hypoxia and carbon dioxid rtention caused by CH which involved the respiratory center and complicated with pulmonary infection may also have effect on the production of T lymphocyte.
出处
《卒中与神经疾病》
1997年第3期138-140,共3页
Stroke and Nervous Diseases
关键词
T细胞亚群
脑出血
多器官衰竭
并发症
T Lymphocyte subpopulation Cerebral hemorrhage Multiple organ failure
