摘要
总结了近几年咪唑啉受体的一些研究情况,包括受体特征、分类及其与α2受体的关系。结合相应的药物阐述了各亚型的药理作用机制,并对咪唑啉受体的一些内源性配基作了简要介绍。
A brief update on imidazoline receptor characterization and subclassification was provided Functionally and pharmacologically, the relation between this receptor and α 2 adrenoceptor was approached . The pharmacological mechanisms of the two receptors subclasses (I 1,I 2)were illuminated with the agents having selectivity. Several endogenous ligands that bind to imidazoline receptors were also discussed.
出处
《药学进展》
CAS
1997年第3期152-157,共6页
Progress in Pharmaceutical Sciences
关键词
咪唑啉
受体
内源性配基
高血压
Imidazoline receptors Mechanism of action Endogenous ligands α 2 Adrenoceptor