摘要
应用PCR及PAG电泳技术研究了PLA2A、vWA、CYP19、TH和LPL五个基因座的多态性，调查武汉地区汉族无关个体，获得汉族人群的频率分布。五个基因座基因型频率分布与Hardy-Weinberg平衡吻合良好、分别计算基因座的杂合度（H）、个人识别能力（Dp）、非父排除率（PE）和多态性信息总量（PIC）。为法医学应用提供了基础数据。
The polymorphic analysis of STR loci PLA2A, vWA, CYP19, TH and LPL in the Han population in Wuhan was studied using PCR and PAG electrophoresis. The allele distributions of the loci were good agreernent with the Hardy-Weinberg equibrium. The H,Dp,PE and PIC of 5 loci were calculated. The method established and the data obtained are useful in forensic science applications.
出处
《中国法医学杂志》
CSCD
1997年第2期69-73,共5页
Chinese Journal of Forensic Medicine
关键词
STR基因座
PCR
基因座
多态性
汉族
亲子鉴定
Short tandem repeat (STR) Polymerase chain reaction (PCR) Gene locus Genetic polymorphism
