1Rosholt AP. The Seventh Amendment directive an unnecessary measure to a necessary end possible legal challenges to directive 2003/15/EC of the European Parliament and of the Council Amending Council Directive 76/768/EEC under European Union law. Food Drug Law J,2005,60: 421- 446. 被引量：1
2Welss T, Basketter DA, Schroder KR. In vitro skin irritation: facts and future. State of the art review of mechanisms and models. Toxicol In Vitro,2004,18: 231-243. 被引量：1
3Corsini E, Viviani B, Zancanella O, et al. Induction of adipose differentiation related protein and neutral lipid droplet accumulation in keratinocytes by skin irritants. J Invest Dermatol,2003,121 : 337-344. 被引量：1
4Sanchez L, Mitjans M, Infante MR, et al. Determination of interleukin-1 alpha in human NCTC 2544 keratinocyte cells as a predictor of skin irritation from lysine-based surfactants. Toxicol Lett, 2006,25. 被引量：1
5Wilhelm KP, Bottjer B, Siegers CP. Quantitative assessment of primary skin irritants in vitro in a cytotoxicity model: comparison with in vivo human irritation tests. Br J Dermatol, 2001,145 : 709-715. 被引量：1
6Lee JK, Kim DB, Kim JI, et al. In vitro cytotoxicity tests on cultured human skin fibroblasts to predict skin irritation potential of surfactants. Toxicol In Vitro,2000,14 : 345-349. 被引量：1
7Sanchez L, Mitjans M, Infante MR, et al. Assessment of the potential skin irritation of lysine-derivative anionic surfactantsusing mouse fibroblasts and human keratinocytes as an alternative to animal testing. Pharm Res,2004,21:1637-1641. 被引量：1
8Kim BH, Lee YS, Kang KS. The mechanism of retinolinduced irritation and its application to anti-irritant development. Toxicol Lett,2003,146 : 65-73. 被引量：1
9Wilhelm KP, Bottjer B, Siegers CP. Quantitative assessment of primary skin irritants in vitro in a cytotoxicity model : comparison with in vivo human irritation tests. Br J Dermatol, 2001,145: 709-115. 被引量：1
10Fentem JH, Briggs D, Chesne C, et al. A prevalidation study on in vitro tests for acute skin irritation, results and evaluation by the Management Team. Toxicol In Vitro,2001,15: 57-93. 被引量：1
3Liebsch M, Spielmann H. Currently available in vitro methods used in the regulatory toxicology. Toxicol Lett, 2002,127 ( 1 -3) :127 ～ 134 被引量：1
4Portes P, Pygmalion M J, Popovic E, et al. Use of human reconstituted epidermis episkin for assessment of weak phototoxic potential of chemical compounds. Photodermatol Photoimmunol Photomed, 2002,18(2) :96 ～ 102 被引量：1
5Kandarova H, Liebsch M, G, enschow E, et al. Optimisation of the EpiDerm test protocol for the upcoming ECVAM validation study on in vitro skin irritation tests. ALTEX, 2004,21 (3):107 ～ 114 被引量：1
6Zissu D. Experimental study of cutaneous tolerance to glycol ethers. Contact Dermatitis, 1995,32 (2) :74 ～ 77 被引量：1
7Fentem J H, Archer G E B, Balls M, et al. The ECVAM international validation study on in vitro tests for skin corrosivity. 2. Results and evaluation by the management team.Toxicol In Vitro, 1998,12:483 ～524 被引量：1
8Jirova D, Kejlova K, Brabec M, et al. The benefits of the 3T3NRU test in the safety assessment of cosmetics: long-term experience from pre-marketing testing in the Czech Republic.Toxicol In Vitro, 2003,17(5- 6) :791 ～796 被引量：1
9Kandarova H,Liebsch M,Genschow E,et al.Optimisation of the EpiDerm test protocol for the upcoming ECVAM validation study on in vitro skin irritation tests[J].ALTEX,2004,21(3):107-114. 被引量：1
10Portes P,Grandidier MH,Cohen C,et al.Refinement of the Episkin protocol for the assessment of acute skin irritation of chemicals:follow-up to the ECVAM prevalidation study[J].Toxicol In Vitro,2002,16(6):765-770. 被引量：1
7Commission of the European Communities. Proposal for a Regulation of the European Parliament and of the Council, Concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH). European Regulation of REACH (VOLUME I) ,2003,1:25. 被引量：1
8Van Der Jagt K, Munn S, Tφrslφv J, et al. Alternative Approaches can Reduce the Use of Test Animals under REACH. IHCP Report, 2004 : 1-31. 被引量：1
9Pedersen F, De Bruijn J, Munn S, et al. Assessment of additional testing needs under REACH. Effects of ( Q ) SARS, risk based testing and voluntary industry initiatives. European Commission Report, 2003 : 1-36. 被引量：1
10Commission of the European Communities. Proposal for a Regulation of the European Parliament and of the Council, Concerning the Registration, Evaluation, Authofisation and Restriction of Chemicals (REACH). European Regulation of REACH (VOLUME Ⅱ-Annexes Ⅰ to IX to the Proposal for a Regulation ), 2003,2 : 48- 80. 被引量：1
