摘要
目的探讨急诊科重症监护病房患者死亡的相关因素。方法上海交通大学医学院附属第九人民医院EICU病房2005年2月至2007年1月共收治患者450例，生存组356例和死亡组94例。对年龄、性别、APACHEⅡ评分、GCS评分、白蛋白、C．反应蛋白、基础疾病、死亡原因以及院内感染等因素进行分析比较。数据以均数±标准差（X^-±s）表示，计数资料采用两独立样本的t检验，两组合并基础疾病数比较采用Radit检验，两组发生院内感染率比较采用f检验。P〈0．05为差异有统计学意义。结果死亡组较生存组年龄大（P=0．002）、合并基础疾病数多（P〈0．05）、APACHEⅡ评分高（P〈0．01）以及GCS评分低（P〈0．01）。死亡组血清白蛋白浓度低（P=0．006）、C-反应蛋白值高（P〈0．01）、合并有院内感染多（P=0．046）。主要的死亡原因为呼吸衰竭和多脏器功能衰竭。结论对危重患者病情进行预后评估，有利于采取有效措施，降低病死率。
Objective To explore the relevant factors to death of patients in Emergency Intensive Care Unit. Method A retrospective study of 450 patients from EICU of the Ninth People＇s Hospital Aflihated to Medical College of Shanghai Jiaotong University was conducted. Among these patients, 356 survived and 94 died. Relevant factors, including age, gender, APACHE 11 score, GCS score, albumin, C-reactive protein, underlaying disease, course of death and nosocomial infection were analyzed. The data were expressed as （x ^-± s ）, and analyzed using student＇ s t test and Radit test and chi-square test. A P value less than 0.05 was considered as significant. Results Compared with survival group, there were older （ P = 0.002）, higher APACHE Ⅱ scores （P〈0.01）, more underlying diseases （P 〈 0.05）, lower GCS scores （P 〈 0.01）, lower levels of serum albumin （ P = 0.006）, higher levels of C-reactive protein （ P 〈 0.01 ） and more nosocomial infections （ P = 0.046） in death group. The main causes of death were multiple organ dysfunction syndrome and respiratory failure. Conclusions By evaluating the severity and the prognosis of patients in ICU, effective measures can be taken to decrease mortality.
出处
《中华急诊医学杂志》
CAS
CSCD
2008年第3期306-309,共4页
Chinese Journal of Emergency Medicine
关键词
急诊ICU
临床分析
血清白蛋白浓度
C-反应蛋白
预后
Emergency Intensive Care Unit
Clinical analysis
Serum albumin concention
C-reactive protein
Prognosis
