摘要
[目的]探讨子宫切除范围及淋巴结清扫术对子宫内膜癌预后的影响。[方法]对102例子宫内膜癌患者,将其中行筋膜外子宫切除手术(筋膜外组)40例与次广泛/广泛子宫切除术(广泛组)62例患者进行对照分析;行盆腔淋巴结清扫术(清扫组)48例和未行淋巴结清扫术(未清扫组)54例进行对照分析,比较其生存率。[结果]102例患者5年总的生存率为93.1%。筋膜外组与广泛组患者5年生存率比较,差异无显著性(P>0.05),但其中Ⅱ期及Ⅱ期以上患者筋膜外组、广泛组的5年生存率分别为66.7%和91.3%,有显著性差异(P=0.044)。单因素分析结果提示盆腔淋巴有转移的患者预后不良。盆腔淋巴结清扫术和未行清扫术两组生存率比较,差异无显著性(P>0.05)。[结论]盆腔淋巴转移的患者预后差,但盆腔淋巴清扫术并不改善患者预后。Ⅱ期及Ⅱ期以上患者行次广泛/广泛子宫切除术有助于改善预后。
[Purpose] To investigate the impact of the surgical dissection extension and lymphadenectomy on prognosis in patients with endometrial cancer. [Methods] Among 120 cases with endometrial cancer, survival rates were compared between intra-fascia hysterectomy （40 cases） and with sub-radical or radical hysterectomy （radical group, 62 cases）, and between pelvic lymphadenectomy （48 cases） and no-lymphadenectomy （54 cases）, [Results] The overall 5-year survival rate in the whole group was 93.1%. There was no significant difference in 5-year survival rate between intra-fascia group and radical group（P〉0.05）, However, in patients with stage Ⅱ and over, 5- year survival between intraascia group （66.7%） and radical group （91.3%） （P=0.0440） was significant difference. Univariate analysis revealed that patients with pelvic lymph node metastasis had poor outcome, But no significant difference was found in survival between lymphodeneetomy group and no-lymphodenectomy group （P〉0.05）. [Conclusionl The endometrial cancer patients with pelvic lymph node metastasis has poor outcome, but pelvic lymphadenectomy can not improve prognosis. Sub-radical/radical hysterectomy may improve progress in patients with stage Ⅱ and over.
出处
《肿瘤学杂志》
CAS
2008年第2期138-140,共3页
Journal of Chinese Oncology
