摘要
目的:探讨非小细胞肺癌(NSCLC)骨转移的中西医治疗方法。方法:回顾性分析200例非小细胞肺癌的临床资料。结果:发生骨转移部位包括肋骨134例(67%)、胸椎118例(59%)、骨盆106例(53%)、腰椎98例(49%)、四肢骨74例(37%)、肩胛骨20例(10%)、胸骨18例(9%)、颅骨23例(11.5%)。128例接受过化疗,98例接受过放射治疗,136例接受过氯屈膦酸二钠治疗,10例接受过核素治疗。发生骨转移后1年生存率为30.6%,生存期为1～26个月,中位生存期为8个月。其中有18例(9%)患者发生病理性骨折,包括四肢长骨12例,椎骨6例。12例四肢骨折当中3例行外科手术内固定,其余9例和椎骨压缩性骨折6例在抗肿瘤治疗的同时运用中医正骨治疗。结论:非小细胞肺癌骨转移的治疗是结合手术、放化疗、双磷酸盐药物等的多学科综合治疗;中医正骨是并发病理性骨折不能耐受手术患者的合适选择。
OBJECTIVE： To evaluate treatment of NSCLC with bone metastasis combined with Chinese traditional medicine. METHODS： To analyse clinical information of 200 cases of NSCLC. RESULTS： 128 cases accepted chemotherapy, 98 cases accepted radiotherapy, 136 cases accepted clodronate clodronate diso dium drugs and 10 of them accepted nuclide therapy. 18 cases complicated with pathological fracture, 3 of them received surgery while other 15 received Chinese traditional bone - setting. CONCLUSION： Muhidisciplinary synthetic therapy include surgery, chemo/radio - therapy, diphosphate drugs are necessary to control bone metastasis of NSCLC. Chinese traditional bone- setting is the proper choice for patient complicated with pathological fracture, especially when they can not tolerate surgery.
出处
《中国医院用药评价与分析》
2008年第1期56-57,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
非小细胞肺癌
骨转移
中西医治疗
正骨
NSCLC
Bone metastasis
Chinese - western medicine
Bone - setting
