摘要
学术背景:单肺通气在心胸外科一般手术和肺移植手术中广泛应用,近几年来有关单肺通气的研究较多。目的:综合分析单肺通气的研究进展,以期提高单肺通气的效果,减少单肺通气期间和单肺通气后并发症的发生。检索策略:应用计算机检索Medline 1980-01/2007-10有关单肺通气的文章,检索词为"one-lungv entilation,hypoxemia,lung transplantation",限定文章语言种类为English。同时计算机检索CNKI数据库2000-01/2007-10有关单肺通气的文章,检索词"单肺通气,低氧血症,肺移植",限定文章语言种类为中文。对资料进行初审,并查找全文。纳入标准:①有关单肺通气的实验及临床研究。②有关肺移植手术麻醉的临床研究。排除标准:①重复研究。②综述文献。共收集到300多篇有关单肺通气方面的文献,纳入28篇。文献评价:纳入的28篇文章中有关单肺通气术中管理方面的文献15篇,有关单肺通气时低氧血症方面的文献13篇。资料综合:通过对入选文献进行分析、整理,将单肺通气术中管理从潮气量与呼吸频率的设置、通气模式选择、吸入氧浓度及液体管理等4方面进行分析。低氧血症是单肺通气面临的最大挑战,通过各种方法可以改善动脉氧合,降低低氧血症的发生率。但是对于术中单肺通气的管理还存在争论,有待进一步研究。结论:随着单肺通气术中管理及常见问题处理方法研究的不断深入,单肺通气的应用将会更加广泛,更加安全。
BACKGROUND： One-lung ventilation is wildly applied in cardiothoracic surgery including general surgery and lung transplantation surgery. There have been much more researches of one-lung ventilation in recent years.
OBJECTIVE： To analyze and conclude the research progress of one-lung ventilation with a view to improve the effectiveness of one-lung ventilation and reduce complications during and after one-lung ventilation.
RETRIEVAL STRATEGY： A computer-based search of Medline was undertaken to identify the articles about one-lung ventilation published from January 1980 to October 2007 with the keywords ＂one-lung ventilation, hypoxemia, lung transplantation＂, and the language was limited to English. Chinese articles about one-lung ventilation punished from January 2000 to October 2007 were searched in China National Knowledge Infrastructure （CNKI）, with the keywords ＂one-lung ventilation, hypoxemia, lung transplantation＂ and the language was limited to Chinese. The materials were selected firstly and full texts were searched. Inclusion criteria： ①the basic and clinical study on one-lung ventilation;②the clinical study on anesthesia of lung transplantation. Exclusion criteria： ①repetitive study;②reviews. Over 300 articles on one-lung ventilation were collected, in which 28 were accordant with inclusion criteria.
LITERATURE EVALUATION： Of the 28 articles, 15 were about the study of the management during one-lung ventilation, and 13 were the hypoxemia study of one-lung ventilation.
DATA SYNTHESIS： After the selected literatures were analyzed and arranged, the management of one-lung ventilation including the selection of ventilation mode, the settings of tidal volume and respiratory frequency, fraction of inspired oxygen, fluid management was analyzed. Hypoxemia is the biggest challenge during one-lung ventilation. We may improve arterial oxygenation and reduce the occurrence of hypoxemia by various ways. However, the management of one-lung ventilation is still controversial and n
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2008年第5期945-948,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
