摘要
目的评价舒芬太尼用于胸外科手术时对血流动力学、术后苏醒时间及血浆中应激物质（去甲肾上腺素、肾上腺素）浓度的影响。方法择期行胸外科手术患者30例，ASAⅠ-Ⅱ级，随机分为舒芬太尼组（S组，n=16）和芬太尼组（F组，n=14），于手术各时间点分别监测血流动力学指标，比较术后苏醒时间和镇痛效果，并测定各时点血浆中的肾上腺素、去甲肾上腺素浓度。结果F组血流动力学变化比S组大（P〈0．05），S组术后苏醒时间短于F组，但镇痛时间长于F组．S组血浆中的。肾上腺素、去甲肾上腺素浓度变化较小。结论舒芬太尼用于长时间的胸外手术中，可维持良好的血流动力学稳定性，苏醒较快，但镇痛效果维持时间长，体内应激性物质产生较少。
Objective To investigate the effects of sufentanil on hemodynamics, extubation and awaking time, and the concentrations of noradrenaline and adrenaline in plasma during anesthesia in thoracic surgery. Methods Thirty ASA Ⅰ-Ⅱ patients undergoing thoracic operation were enrolled and randomly allocated to receive sufentanil（S group, n = 16）and Fentanil（F group, n = 14）and the data of hemodynamics, extubation and awaking time, and the concentrations of nor,adrenaline and adrenaline in plasma were compared between the two groups. Results The changes in data of hemodynamics in F group were significantly greater than those in S group （P〈0.05）. In S group, the awaking was shorter,analgesic time longer, and less changes in concentrations of plasma noradrenaline and adrenaline than in F group. Conclusions Sufentanil used in anesthesia for thoracic surgery decreases hemodynamics imbalance, reduces the concentrations of plasma noradrenaline and adrenaline, and elicits shorter extubation and awakening time but longer analgesic time.
出处
《武警医学》
CAS
2008年第2期153-156,共4页
Medical Journal of the Chinese People's Armed Police Force
关键词
舒芬太尼
芬太尼
胸外科麻醉
血流动力学
Sufentanil Fentanyl Thoracic surgery Anesthesia Hemodynatnies
