摘要
目的探讨结节病的临床特点和诊断方法。方法回顾分析解放军总医院自1996年来经组织病理学确诊的67例结节病患者的临床资料。结果女性多于男性,男∶女为1∶2.0,平均发病年龄47.1岁。其中0期5例,Ⅰ期26例,Ⅱ期33例,Ⅲ期3例。呼吸道症状以咳嗽胸闷气促最多,分别占52.2%(35/67)、41.8%(28/67)和38.8%(26/67)。全身症状主要为乏力消瘦(28.4%)和发热(20.1%)。血清血管紧张素转换酶阳性率为83.0%。经气管镜支气管黏膜活检和肺组织活检阳性率分别为78.6%和72.7%,纵隔镜活检阳性率100%。结论结节病临床表现无特异性,对有肺门纵隔淋巴结肿大的可疑病例,应尽可能作组织病理学检查明确诊断。
Objective To explore the clinical features and diagnosis of sarcoidosis. Methods Clinical materials of 67 consecutive patients with biopsy-proven sarcoidosis were retrospectively analyzed. Results There were more female patients than males and the ratio of males to females was 1 ： 2.0. The average age was 47. 1 years. There were 5, 26, 33 and 3 cases in stage 0, Ⅰ, Ⅱ and Ⅲ respectively. The main symptoms of respiratory tract included cough （52.2%）, chest distress （41.8%） and anhelation （38.8%）. The main general symptoms included hypodynamia, emaciation and fever. Eighty-three per cent of the patients had high levels of serum angiotensin converting enzyme. The diagnosis was confirmed in 78.6 % by the transbronchical mucosa biopsies and 72.7% by the transbronchial lung biopsies. The diagnosis was confirmed in 100% by lymph node biopsy through mediastinoscopy. Conclusion No specific clinical manifestation may occur in the cases of sarcoidosis. Pathological examination should be made for the prevention of missed diagnosis and misdiagnosis.
出处
《中华老年多器官疾病杂志》
2008年第1期36-39,共4页
Chinese Journal of Multiple Organ Diseases in the Elderly
