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解郁活血法治疗抑郁症45例临床观察 被引量:15

Clinical Observation on 45 Cases of Depression Treated by Soothing Stagnation and Invigorating Blood Circulation
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摘要 目的观察疏肝解郁、活血化瘀法治疗抑郁症的临床疗效。方法将90例抑郁症患者随机分为治疗组45例和对照组45例。治疗组以舒肝解郁、活血化瘀为治疗原则,给予逍遥散加减,对照组给予氟西汀治疗,共治疗8周。记录并比较治疗前后各组抑郁自评量表(SDS)、汉密顿抑郁量表(HAMD)、副反应量表(TESS)和中医症状评分。结果治疗组SDS、HAMD、TESS、中医症状评分均较治疗前明显改善(P<0.05或P<0.01);治疗后两组间比较差异不显著,但不良反应明显低于对照组(P<0.01)。结论解郁活血法治疗抑郁症疗效显著、药效安全、副作用小。 Objective To observe the therapeutic effect of the method of soothing liver qi stagnation and invigorating blood circulation to remove stasis for depression. Methods Totally 90 depression cases were randomized into treatment group and control group with 45 in each, The treatment group was given modified Xiaoyao Powder(Powder for liver qi stagnation with blood stasis) based on the principle of soothing liver qi stagnation to remove stasis. The control group was given Fluoxetine. The course of treatment was 8 weeks in all. Self-rating Depression Scale (SDS), Hamilton Depression Scale (HAMD), Treatment Emergent Symptom Scale (TESS) and scores of TCM symptoms before and after treatment were recorded for comparison. Results SDS, HAMD, TESS and TCM symptoms were improved after treatment in the treatment group (P〈0.05 or P〈0.01). The untoward reaction was obviously lower in the treatment group than that of control group (P〈0. 01). Conclusion The effect of soothing liver qi stagnation and invigorating blood circulation to remove stasis for depression is remarkcble, safe and side effect less.
出处 《中医杂志》 CSCD 北大核心 2008年第1期41-42,52,共3页 Journal of Traditional Chinese Medicine
关键词 抑郁症 中医药疗法 解郁 活血 Depression TCM treatment Soothing stagnation Invigorating blood circulation
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