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胸腰段脊柱结核围手术期营养支持的临床对照试验 被引量:9

A controlled clinical trail of perioperative nutritional support of thoracolumbar spinal tuberculosis
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摘要 目的:探讨营养支持对围手术期胸腰段脊柱结核患者的营养状况的影响。方法:符合纳入标准的48例胸腰段脊柱结核患者,男25例,女23例;年龄35~60岁,平均48.25岁。按就诊顺序随机分成2组(试验组和对照组),每组24例。试验组从术前7d至术后7d在普通饮食基础上通过静脉途径增加营养供给,对照组只给予普通饮食。术前7d和术后7d对2组患者的体重、血浆清蛋白浓度、血沉进行比较。并比较2组术后伤口引流液总量。结果:试验组术后体重和血浆清蛋白浓度与术前比较,差异无统计学意义(P>0.05);对照组术后体重和血浆清蛋白浓度比术前低,差异有统计学意义(P<0.05)。试验组术后伤口引流液总量比对照组少,差异有统计学意义(P<0.05)。试验组和对照组术后血沉较术前均有下降(P<0.05),但试验组的血沉降幅比对照组大,差异有统计学意义(P<0.05)。结论:有效的营养支持有利于减轻手术和结核杆菌造成的机体营养不良,有助于增强手术和抗痨药物的疗效。 Objective :To evaluate the influence of perioperative nutritional support on nutritional status of patients with thoracolumbar spinal tuberculosis. Methods: Forty-eight patients with thoracolumbar spinal tuberculosis (male 25 and female 23, aged from 35 to 60 years, with an average of 48.25 years )were randomized into two groups. Twenty-four patients nutritional support were increased intravenously for 14 days (7 days before and after operation )in experimental group. Twenty-four patients in control group were supplied with routine diet. The body weight ,plasma concentrations of albumin and ESR were detected on the 7th day before operation and on the 7th day after operation. The total wound drainage was recorded and compared. Results : Body weight and plasma concentrations of albumin on the 7th day after operation and those on the 7th day before operation were not significantly different in experimental group ( P〉0.05 ). In control group, body weight and plasma concentrations of albumin on the 7th day after operation was lower than those on the 7th day before operation ( P〈0.05 ). The total wound drainage of experimental group was less than that of control group( P〈0.05 ). ESR on the 7th day after operation was lower than that on the 7th day before operation in two groups(P〈0.05) ;but the decrease of ESR in experimental group was more than that in control group P〈0.05 ). Conclusion : Nutritional support is beneficial to alleviating innutrition caused by tubercle bacillus and operation. It can promote the effects of operation and anti-tuberculotic drugs.
出处 《中国骨伤》 CAS 2008年第1期28-29,共2页 China Journal of Orthopaedics and Traumatology
关键词 脊柱结核 围手术期 营养支持 临床对照试验 Spinal tuberculosis Perioperative Nutritional support Controlled clinical trails
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