摘要
目的了解机械通气患者中急性肾衰竭(ARF)的发生率,总结其临床特征。方法采用病例报告表,回顾性收集我院呼吸内科重症监护病房(ICU)由2000-01～2006-12收治的88例机械通气患者的主要临床参数,建立数据库。根据是否发生ARF分组,采用t检验和χ2检验分析两组之间的差异。结果机械通气患者中ARF的发生率为36.4%(n=32)。在并发ARF的机械通气患者,ICU时疾病严重程度(APACHEⅡ评分)、耐药病原体感染、出现休克和机械通气相关性肺炎、使用血管收缩药物和糖肽类抗生素的患者比率均明显高于没有并发ARF的患者。结论机械通气患者并发ARF的危险性很高,针对具有高危因素的患者,采取积极的防范措施具有重要的实际意义。
Objective To evaluate the incidence of acute renal failure（ARF）in the patients requiring mechanical ventilation and the role of potential risk factors in the development of ARF.Methods From January 2000 to December 2006,88 patients who were admitted to our pulmonary ICU and required mechanical ventilation were included in this retrospective cohort study.The clinical characteristics,pathogens,therapies and complications during ventilation and other known risk factors for development of ARF were evaluated.Risk factors were analyzed by t-test and χ^2 test for significance.Results The incidence of ARF was 36.4%（n=32）in our cohort.Pneumonia with methicillin-resistant Staphylococcus aureus,development of shock and sepsis,severity of primary disease（Acute Physiology and Chronic Health Evaluation II score）,use of glycopeptide and vasopressors were potential risk factors for the development of ARF during mechanical ventilation.Conclusion These results showed that the incidence of ARF is high during the mechanical ventilation.Active protection and effective treatments should be carried out in the patients with high risk of ARF.
出处
《中国急救医学》
CAS
CSCD
北大核心
2008年第1期63-65,共3页
Chinese Journal of Critical Care Medicine
关键词
急性肾衰竭
重症监护室
机械通气
危险因素
Acute renal failure
Intensive care unit
Mechanical ventilation
Risk factor
