摘要
目的：研究氦氖激光的生物学效应。方法：用３４．５～１３８Ｊ／ｃｍ２的氦氖激光照射体外培养的人肝癌ＳＭＭＣ７７２１和人胃癌ＳＧＣ７９０１细胞，间日１次，共６次。结果：６９Ｊ／ｃｍ２和１３８Ｊ／ｃｍ２的氦氖激光照射人肝癌细胞后７２小时和９６小时内、３４．５～１３８Ｊ／ｃｍ２的氦氖激光照射人胃癌细胞后７２小时内有促进增殖的作用（Ｐ＜０．０５）。结论：较大剂量的氦氖激光照射人癌细胞后在一定时间内有促进其生长的作用，在临床应用上应避免该副作用的发生。
Objective: To gain insight into the biological effects of helium neon laser on cells.Methods: Cultured human hepatoma and gastric cancer cells were treated to assess the effects of low energy helium neon laser irradiation( 34.5 ￣138 J/cm 2,once in every other day,for 6 times) on cell proliferation. Results:A significant stimulative effect on proliferation was found statistically in both hepatoma (69 J/cm 2 within 72 hours and 138 J/cm 2 within 96 hours post irradiation) and gastric cancer cells( 34.5 ￣138 J/cm 2 within 72 hours after irradiation)(P< 0.05 ). Conclusion : The results suggest that helium neon laser irradiation in patients with hepatoma and gastric cancer or after oncologic surgery could be potentially harmful as result of stimulating proliferation.
出处
《中华物理医学杂志》
CAS
CSCD
1997年第2期69-71,共3页
Chinese Journal of Physical Medicine and Rehabilitation
基金
国家自然科学基金
关键词
肝肿瘤
放射疗法
胃肿瘤
细胞转化
激光疗法
lasers/ther use
lasers/adv eff
liver neoplasms/radiother
stomach neoplasms/radiother
cell transformation,neoplastic/rad eff
cells,cultured
human
