摘要
目的探讨股骨头坏死0期临床诊断标准的建立,并通过临床应用验证其准确性和临床价值。方法回顾性分析临床非创伤性股骨头坏死患者258例,建立非创伤性股骨头坏死0期临床诊断标准,并根据该标准进行临床对照研究。结果所建立标准的灵敏度、特异度、准确度分别为93.7%、86.4%、89.7%。临床应用研究显示给予预防性治疗(干预组)的患者,其股骨头坏死发生率明显低于无干预组(34.2%vs84.9%,P<0.01)。结论确立了非创伤性股骨头坏死0期临床诊断标准,有助于早期发现股骨头坏死,具有重大的临床应用价值;同时发现对0期非创伤性股骨头坏死应用多种预防性综合措施进行干预,治愈率较高,能有效降低股骨头坏死的发病率。
Objective To establish clinical diagnostic criteria for zero-stage non-traumatic osteonecrosis of femoral head,and then to check the accuracy and value of the criteria in clinical application through combined intervention therapy including the administration of traditional Chinese medicine and physical therapy.Methods The clinical data of 258 patients suffering from non-traumatic osteonecrosis of femoral head were retrospectively analyzed.Clinical diagnostic criteria for zero-stage non-traumatic osteonecrosis of femoral head were established based on the analysis.Then a clinical comparative study concerning the criteria was performed,so as to verify its authority.Results The established criteria were proved to be satisfactory.The sensitivity,specificity and accuracy of the criteria were 93.7%,86.4% and 89.7%,respectively.The clinical comparative study showed that the prevalence of non-traumatic osteonecrosis of femoral head in the intervention group（34.2%）was obviously lower than that of the non-intervention group（84.9%,P〈0.01）.Conclusion The clinical diagnostic criteria for zero-stage non-traumatic osteonecrosis of the femoral head are established,which are helptul in early discovery and prophylactic treatment for the ailment.Treated with combined preventive intervention,the zero-stage non-traumatic osteonecrosis of femoral head could be cured with a high cure rate,and the prevalence of the femoral head osteonecrosis was obviously decreased.
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2007年第12期1224-1225,共2页
Medical Journal of Chinese People's Liberation Army
基金
全军"十五"医学科研基金指令性课题(04LX010)
关键词
股骨头坏死
0期诊断标准
回顾性研究
治疗
临床研究性
femur head necrosis,zero-stage diagnostic criteria,retrospective studies,therapies,investigational
