摘要
目的:探讨18F-FDGPET-CT对头颈部肿瘤治疗后复发及转移的临床诊断价值。方法:对42例经治疗、且临床无法确诊是否复发和转移的头颈部肿瘤患者行18F-FDGPET-CT显像,所有病灶都进行临床随访或病理学检查,以诊断是否符合随访结果作为判断标准。将PET-CT诊断结果与同期CT结果作对照分析。结果:PET-CT诊断异常病灶103个。CT检查的敏感度、特异度和诊断符合率分别为92.55%、42.11%和84.07%,PET-CT分别为100.00%、52.63%和92.04%。PET-CT与CT检查的敏感度、诊断符合率比较差异均有统计学意义(P<0.05或P<0.01),而特异度差异无统计学意义(P>0.05)。结论:18F-FDGPET-CT对头颈部肿瘤的主要优势在于鉴别治疗后瘢痕与肿瘤复发、淋巴结及远处脏器转移。PET-CT诊断之前需详细了解临床资料以及形态学检查结果,并且治疗与检查的间隔时间不应小于6周。
Objective：To explore the significance of ^18F-FDG PET-CT in the diagnosis of the recurrence and metastasis of head-and-neck tumor after definitive treatment. Method：Forty-two patients having received definitive treatment for head-and-neck tumor of whom the tumor could not be identified clinically underwent ^18F-FDG PET- CT examination. Follow-up data could be obtained for all loci identified on PET-CT images. PET-CT and CT accuracy was compared on the basis of follow-up and histopathologic findings. Result： A total of 103 loci were noted on PET-CT images. Identified by follow-up data, the sensitivity, specificity and accuracy were 92.55%, 42.11% and 84.07% respectively for CT examination, and 100.00%, 52.63%, and 92.04% for PET-CT respectively. The sensitivity and accuracy of PET-CT were significantly higher than those of CT （P〈0. 05 or P〈0. 01）, whereas the difference in specificity between the results of these two groups was not significant（P〉0.05）. Conclusion：The major benefits of FDG PET were that it differentiates scar and relapse, as well as detects LN and distant metastasis. Detailed clinical information and inclusion of results of morphological diagnostics are prerequisites for PET-CT final image interpretation, while scans should not be performed less than 6 weeks after definitive treatment.
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2008年第1期18-21,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
