摘要
目的：探讨2型糖尿病患者并发脑梗死与颈动脉粥样硬化的关系。方法：对37例2型糖尿病合并脑梗死患者行颈动脉超声检查,检测颈动脉内膜-中膜厚度,颈动脉斑块面积、性质及动脉管腔狭窄程度。结果：2型糖尿病合并脑梗死与颈动脉粥样硬化斑块有明显的关系,糖尿病组有32例检查出粥样硬化斑块,而对照组仅有19例,斑块导致颈动脉狭窄多为轻、中度,重度狭窄较少,而且梗死灶的部位与颈动脉粥样硬化斑块有明显的同侧性（P〈0.005）,颈动脉粥样硬化斑块随着糖尿病病程的增长而增加（P〈0.005）,与血糖、血脂、纤维蛋白原有一定关系（P〈0.05-P〈0.001）。结论：2型糖尿病合并脑梗死大多有颈动脉粥样硬化斑块,对糖尿病患者进行脑血管病的一级预防及脑梗死与2型糖尿病的治疗及二级预防有重要的临床意义。
Objective：To explore the relationship between cerebral infarction acompanied by type 2 diabetes mellitus and carotid atherosclerosis. Methods：The intima-media thickness of the carotid artery, the area and quality of carotid plaque and the level of stenosis of artery were measured in 37 cerebral infarction patients combined with type 2 diabetes mellitus using carotid artery ultrasound. Results： Cerebral infarction combined with type 2 diabetes mellitus was obviously correlated with carotid atherosclerosis plaques. Atherosclerosis plaques was found in 32 cases in the diabetes group, and only 19 cases in the contral group;and the plaques rarely caused severe stenosis of carotid artery （ P 〈 0. 005 ）. The infarction position was obviously homolateral to the carotid atherosclerosis. As the time of diabetes meuitus prolonged, the appearance of carotid atherosclerosis plaques increased, which might be related with blood glucose, blood lipids and fibrinogen （ P 〈 0.05 - P 〈 0. 001 ）. Conclusions ： Most patients with cerebral infarction combined with type 2 diabetes mellitus had carotid atherosclerosis plaques. It is of clinical value to prevent cerebral vascular disease in patients with diabetes mellitus and provide proper treatment for patients with cerebral infarction complicated with type 2 diabetes mellitus.
出处
《蚌埠医学院学报》
CAS
2008年第1期61-63,共3页
Journal of Bengbu Medical College
关键词
糖尿病
2型
脑梗死
动脉粥样硬化
diabetes mellitus, type 2
cerebral infarction
atherosclerosis
