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黏附分子与鼻咽癌的侵袭和转移

Adhesion molecules and nasopharyngeal carcinoma invasion and metastasis
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摘要 黏附分子是一类由细胞产生的膜表面糖蛋白。多项研究已证实,黏附分子可介导肿瘤细胞与细胞外基质、血管内皮细胞、淋巴细胞或其他肿瘤细胞之间的相互作用,因此在恶性肿瘤的侵袭和转移过程中起着重要作用。近年来,已有大量关于黏附分子表达水平的变化可抑制或促进鼻咽癌转移的研究。 Adhesion molecules are membrane surface glycoproteins produced bycells. Many studies have comfirmed that adhesion molbecules can mediate the interaction among tumor cells and extracellular matrix, blood vessel endothelial cells, lymphocytes and other tumor cells, so they play a key role in tumor invasion and metastasis. In recent years,there are a lot of studies that changes in expression of adhesion molecules can inhibit or promote nasopharyngeal carcinoma progession.
出处 《国际肿瘤学杂志》 CAS 2008年第1期20-23,共4页 Journal of International Oncology
关键词 鼻咽肿瘤 细胞黏附分子 Nasopharyngeal neoplasms Cell adhesion molecules
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