摘要
目的:观察急性脑卒中血中ET含量,血脂水平以及两者的关系。方法:急性脑卒中病人于病后3日内取血,部分病人于病后3周复查。ET用放免法测定,血脂用酶法测定。结果:67例脑梗塞和27例脑出血ET含量明显升高,与对照组比较有显著差异。其中50例脑梗塞于病后三周复查,ET较急性期高,并具有统计学意义。直线相关分析显示ET与TC,TG,LDL-CH呈正相关.结论:急性脑卒中病人血中ET升高,提示ET与血脂增高在脑血管病发生和发展中起重要作用。
levels of Endonthelin(ET) were measured by radioimmunoassay in 67 patients of cerebral infarction (CI), 27 patients of cerebral hemorrhage (CH) and 20 healthy Persons. Meanwhile total cholesterol(TC), triglycerides (TG) and HDL-ch, LDL-ch were also measured. There was a marked elevation in plasma ET in the patients 0f CI and CH. Compared with those in control group there has significant difference. Among of them plasma ET in 50patients of CI were measured again in subacute stage. There was trend to elevated levels in that time.The plasma ET concentration was correlated with TC, TG, LDL-ch concentration in cerebral hemorrhage.
出处
《脑与神经疾病杂志》
1997年第3期152-153,173,共3页
Journal of Brain and Nervous Diseases