期刊文献+

沙培林联合碘化油乳剂治疗原发性肝癌的临床应用研究 被引量:3

The clinical study of Sapylin-lipiodol emulsion in treating patients with hepatocellular carcinoma
下载PDF
导出
摘要 目的探讨沙培林联合碘化油乳剂在原发性肝癌治疗中的应用价值。方法对59例原发性肝癌患者分实验组及对照组,分别进行沙培林TACE治疗及常规TACE治疗,对术后反应及疗效进行对比分析。结果术后实验组在治疗效果、肝功能、生存率上优于对照组,副作用两组大致相同。结论沙培林碘化油乳剂免疫栓塞治疗中晚期肝癌是一种安全可行的治疗方法。 Objective To analyze the value of transarterial immunoembolization with an emulsion of streptococcal agent Sapylln and lipiodol in treating patients with hepatocellular carcinoma. Methods 59 patients with hepatocellular carcinoma were divided into two groups: test group and control group. Test group were cured with the streptococcal agent Sapylin and lipiodol, control group were cured with the common chemical drug and lipiodol. The differenceof the reaction and curative effect in the near future were studied. Results The effective of treatment, liver function and survivial rate of test group resembling those after transarterial chemoembolization were better than those of control group, the side effcet after treatemnt was the smae be-tween two groups. Conclusion It is a safe and feasible therapeutic modality that transarterial immunoembolization with an emulsion of streptococcal agent Sapylin and lipiodol in treating patients with hepatocellular carcinoma.
出处 《广州医药》 2008年第1期48-50,共3页 Guangzhou Medical Journal
基金 广东省社会发展领域科技计划项目 编号:73114
关键词 沙培林 原发性肝癌 临床应用研究 Spaylin Hepatocellular carcinoma Clinical study
  • 相关文献

参考文献10

  • 1Huang GT, Yang PM, Sheu JC, et al. Intratumor injection of OK -432 for the treatment of small hepatocellular carcimoma [ J ]. Hepatogastroenterology, 1990,37 (5) : 452 - 456. 被引量:1
  • 2Shirai M, Watanbe S, Nishika M, et al. Intratumoral injection of OK -432 and lymphokine activated killer activity in peripheral blood of patients with hepatocellular carcinoma [J]. EurJ Cancer, 1990, 26:965-967. 被引量:1
  • 3薛德文,刘素贞,宋金龙,丛宁.沙培林联合抗癌药肝动脉灌注治疗中晚期肝癌的疗效分析[J].肿瘤研究与临床,2004,16(5):337-338. 被引量:5
  • 4Tang ML, Hale LP, Sleeber DA, et al. L - selectin is involved in lymphocyte migration to sites of inflammation in the skin : delayed rejection of allografter in L - selectin - deficient mice [J]. J Immunol, 1997, 158:5191- 5194. 被引量:1
  • 5Wu J, Barisoni D, Armato U. An investigation into the mechanisms by which human dermis does not significantly contribute to the rejection of allo - skin grafts [ J ]. Burns, 1995, 21:11 -13. 被引量:1
  • 6董培德,侯明星,孙晓风,贾广志,柏敏霜.沙培林联合化疗药物介入治疗晚期肝癌临床观察[J].中国肿瘤临床,2001,28(2):151-152. 被引量:10
  • 7Oka M, Hazama S, Yoshino S, et al. Intraarterial combined immunchemotherapy for unresectable hepatocellular carcinoma: preliminary suhs [J]. Cancer Immunol Immunother, 1994, 38:194 - 197. 被引量:1
  • 8Castells A, Bruix J, Aynso C, et al. Transarterial embolization for hepatocellular carcinoma: antibiotic prophylaxis and clinical meaning in postembolization fever [ J]. J Hepatol, 1995, 22:410-415. 被引量:1
  • 9叶强,张大海,顾伟中,汝复明,童乾纲,奚顺法.经肝动脉沙培林碘化油乳剂治疗原发性肝癌临床观察[J].同济大学学报(医学版),2001,22(5):33-35. 被引量:8
  • 10Berg DH, Carrasco CH, Hohn DC, et al. Hepatic chemoembolization or embolization for primary or metastic liver tumor: post - treatment management and complications [J]. J Surg Oncol, 1995, 60:116 -121. 被引量:1

二级参考文献10

  • 1长安,陈雪华.沙培林抗肿瘤的实验研究[J].中国实验临床免疫学杂志,1995,7(5):3-7. 被引量:3
  • 2全家妩,李斯勤.乙型链球菌抗癌剂研究及使用现状[J].医药导报,1996,15(4):182-185. 被引量:2
  • 3赵家美 廖美琳 等.沙培林对癌性胸腔积液的疗效观察[J].中华结核和呼吸杂志,1994,(17):161-161. 被引量:18
  • 4中华人民共和国卫生部医政司.中国常见恶性肿瘤诊治规范第二分册:原发性肝癌[M].北京:北京医科大学中国协和医科大学联合出版社,1991.. 被引量:1
  • 5Uchida A. Lysis of fresh human tumor by cytokines released from lymphocytes and its augmentation by the streptococcal preparation OK- 432. [M]// Micksche M,Klein E.OK- 432 A biological response modifier. Thomson Professional postgraduate services, 1986: 3 被引量:1
  • 6Torisu M, Katano M, Kimura Y, et al. New approach to management of malignant ascites with a streptococcal prepatation. OK-432:l.Improvement of host immunity and prolongation of survival[J]. Surgery, 1983,93(3):357-367. 被引量:1
  • 7Ishida N. Immunopoteniating activities of OK-432. Recent advances in the understanding of its mechanism of action[J].Excerpta Medical, 1986, (1): 41-84. 被引量:1
  • 8Imaoka S, Sasaki Y, Ishikawa O, et al.Immunochemotherapy in human hepatocellular carcinoma using the streptococcal agent OK-432[J]. J Clin Oncol, 1986, 4(11): 1645-1651. 被引量:1
  • 9Oshimi K, Kano S, Takaku F, et al. Augmentation of mouse natural killer cell activity by a streptococcal preparation,OK-432 [J]. J Natl Cancer Inst,1980, 65(6):1265-1269. 被引量:1
  • 10张天泽 徐光炜.肿瘤学[M].天津:天津科学技术出版社,1998.1446. 被引量:106

共引文献13

同被引文献13

  • 1黄爱梅,罗莎莉.肝癌介入治疗病人生存质量的影响因素及其护理[J].护理研究(上旬版),2005,19(9):1701-1704. 被引量:10
  • 2Huang GT,Yang PM,Sheu JC,et al.lntratumor injection of Ok-432 for the treatment of small hepatocellular carcimoma. Hepatogastroenterology[J], 1990,37 ( 5 ) : 452-456. 被引量:1
  • 3Wu J.Barisoni D,Armato U.An investigation into the mechanisms by which human dermis does not significantly contribute to the rejection of atto-skin grafts. Bums[J], 995,21 : 1 T - T 3. 被引量:1
  • 4Oka M,Hazama S Yoshino S et al.ln'craarterial combined immu chemotherapy for unresectable hepatocellular carcnoma:pre m nary suits.Cancer Immunol Immunother[J], 1994 38:194-1 97. 被引量:1
  • 5Huang GT,Yang PM,Sheu JC,et al.Intratumor injection of OK-432 for the treatment of small hepatocellular carcimoma[J].Hepatogastroenterology,1990,37(5):452-456. 被引量:1
  • 6Oka M,Hazama S,Yoshino S,et al.Intraarterial combined immu chemotherapy for unresectable hepatocellular carcinoma:preliminary results[J].Cancer Immunol Immunother,1994,38:194-197. 被引量:1
  • 7Miyzaki K,Yasamoto K,Yano T,et al.Synergistic effect of Nocadia rubra cell wall skeleton and recombinant interleukin-2 for in vivo induction for lymphokine activated killer cells[J].Cancer Res,1991,51(19):5261-5265. 被引量:1
  • 8Innmura N,Sone S,Ogana T,et al.Human blood monocyte activation by Nocadia rubra cell wall skeleton for production of interleukin-I and tumor necrosis factor-alpha[J].Biotherapy,1992,4(2):155-159. 被引量:1
  • 9董培德,侯明星,孙晓风,贾广志,柏敏霜.沙培林联合化疗药物介入治疗晚期肝癌临床观察[J].中国肿瘤临床,2001,28(2):151-152. 被引量:10
  • 10李伟,张大海,叶强,顾伟中,汝复明,童乾纲,奚顺法.沙培林碘化油乳剂免疫栓塞治疗原发性肝癌的安全性和不良反应[J].介入放射学杂志,2001,10(2):92-94. 被引量:9

引证文献3

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部