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可卡因-苯丙胺调节转录肽与肥胖关系研究进展 被引量：2

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摘要 可卡因-苯丙胺调节转录肽(cocaine-and amphetamine-regulated transcript peptides,CART)是近年来发现的一种内源性神经肽,参与人和动物多方面的生理功能。CART在进食行为和体内能量调节方面的作用受到广泛的关注,本文就CART的分布、结构特点及其与肥胖关系的研究进展作一综述。
作者 邹赢锌 黄矛 由振东
机构地区 第二军医大学基础部新药评价中心 第二军医大学基础部神经生物学教研室
出处 《癌变．畸变．突变》 CAS CSCD 2008年第1期76-78,共3页 Carcinogenesis,Teratogenesis & Mutagenesis
基金 国家重点基础研究发展计划(973计划2003CB515400)课题七(2003CB515407)
关键词 可卡因-苯丙胺调节转录肽(CART) 进食 肥胖
分类号 R977.1 [医药卫生—药品]
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参考文献29

  • 1Spiess J, Villarreal J, Vale W. Isolation and sequence analysis of a somatostatin-like polypeptide from ovine hypothalamus [J]. Biochemistry, 1981,20(7) : 1982- 1988. 被引量：1
  • 2Douglass J, Mckinzie AA, Couceyro P. PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine [J] . J Neurosci, 1995, 15(3 Pt 2): 2471 - 2481. 被引量：1
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  • 5Smith Y, Koylu EO, Couceyro P, et al. Ultrastructural localization of CART (cocaine- and amphetamine-regulated transcript) peptides in the nucleus accumbens of monkeys [ J ]. Synapse, 1997, 27 (1) : 90 - 94. 被引量：1
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  • 7Wierup N, Kuhar M, Nilsson BO, et al. Cocaine- and amphetamine- regulated transcript (CART) is expressed in several islet cell types during rat development [J] . J Histochem Cytochem, 2004, 52(2): 169- 177. 被引量：1
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  • 9Risold PY, Bemard-Franchi G, Collard C, et al. Ontogenetic expression of CART-peptides in the central nervous system and the periphery: a possible neurotrophic role? [J]. Peptides, 2006, 27(8):1938-1941. 被引量：1
  • 10Bannon AW, Seda J, Carmouche M, et al. Multiple behavioral effects of cocaine- and amphetamine-regulated transcript (CART) peptides in mice: CART 42- 89 and CART 49- 89 differ in potency and activity [J]. J Pharmacol Exp Ther, 2001, 299(3):1021-1026. 被引量：1

同被引文献17

  • 1杨淑萍,谭会泽.畜禽采食调控的研究进展[J].广东饲料,2004,13(5):19-21. 被引量：7
  • 2Spiess J, et al.Isolation and sequence analysis of a so matostatin-like polypeptide from ovine hypothalamus[J]. Biochemistry, 1981,20:1982-1988. 被引量：1
  • 3Douglass J, et al. PCR differential display identifies a rat brain mRNA that is transcriptionally reg ul ated by co caine and amphetamine [J]. J Neurosci, 1995, 15: 2471-2481. 被引量：1
  • 4Philip J L, et al. Chronic Intracere broventricular Ad ministration of Recombinant CART (42-89) Peptide In hibits Food Intake and Causes Weight Loss in Lean and Obese Zucker(fa/fa) Rats[J]. Obesity Research,2000,8:8-9. 被引量：1
  • 5Park JY, et al. Stagedependent regulation of ovarian pituitary adenylate cyclase-activating polypeptide mRNA levels by GnRH in cultured rat granulosa cells. En docrinology,2001,142:3828-3835. 被引量：1
  • 6Upadhya MA, et al. Evidence for the participation of cocaine and amphetamine-regulated transcript peptide (CART) in the fluoxetine-induced anti-hyperalgesia in neuropathic rats[J].Peptides,2011,32(2):317-326. 被引量：1
  • 7Lihua Lv, et al. Effects of sperm capacitation treatments and in vitro culture systems on development of in vitro fertilized embryos derived from prepubertal Boer goat oocytes[J].Asian Australian Journal of Animal Sciences, 2009,22 (7): 969-976. 被引量：1
  • 8Lihna Lv, et al. Effect of oocyte selection, estradiol and antioxidant treatment on in vitro maturation of oocytes collected from prepubertal Chinese Boer goats[J].Italian Journal of Animal Sciences, 2010,9:50-54. 被引量：1
  • 9Kobayashi Y, et al. Evidence that cocaine and amphetamine-reg ul ated transcript is a novel intraovarian regulator of follicular atresia[J].Endocrinology,2004,145 (11):5373-5383. 被引量：1
  • 10Sen Aritro, et al. Cocaine and Amphetamine Reg ul at ed Transcript (CART) Accelerates the Temination of FSH-Induced ERK1/2 and AKT Activation by Regulating the Expression and Degradation of Specific MAP Kinase Phosphatases[J].Mol Endocrinol 2008,22: 2655-2676. 被引量：1

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癌变．畸变．突变
2008年 第1期

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