摘要
【目的】探讨胸部正位摄片对新生儿免疫功能的影响,以期为胸部摄片的选择和防护提供科学依据。【方法】35例可疑肺炎新生儿,分别于胸部正位摄片前及入院后第3 d、第7 d和生后42 d采用流式细胞术、速率散射比浊法检测细胞免疫(包括CD3+T%,CD4+T%,CD8+T%,CD4+T/CD8+T)、体液免疫(包括IgG、IgMI、gA)指标,统计学分析摄片前后各指标的差异。【结果】各指标的时程变化与对照组相比差异均无显著性,但实验组生后42 d CD3+T%明显高于对照组(t=2.047,P<0.05)。【结论】胸部正位摄片对新生儿的免疫功能无抑制作用,并在一定程度上促进了外周血淋巴细胞的成熟和分化。
[Objective] To investigate the influence of chest radiography on newbornstimmune functions. [Methods] Blood samples were taken from 35 newborns with suspicious pneumonia before chest radiography,2^th and 7^th days after hospitalization, 42 days after birth. The T-lymphocyte subpopulation （CD3^ ＋ T %, CD4 ^＋ T % ,CD8^＋ T %, CD4^ ＋ T/CD8^＋ T）and humoral immunity indexes（IgG,IgM,IgA）were measured by flow cytometry and rate nephelometry assay separately. The datas of the treatment and the control groups were analyzed statistically. [Results] The time changes of all the immunity indexes didn＇t show obvious differences from the control group. CD3^＋ T% of the treatment group showed obvious differences from the control group on 42 days after birth. [Conclusions] Chest radiography do not inhibit the immune functions of newborns but accelerate the maturation and differentiation of lymphocytes in the peripheral blood.
出处
《中国儿童保健杂志》
CAS
2008年第1期45-46,50,共3页
Chinese Journal of Child Health Care
