摘要
采用１∶１配比病例对照研究讨论了糖尿病控制程度与糖尿病视网膜病变的关系。以曾经最高血糖值、平均空腹血糖和是否发生过酮症酸中毒反映糖尿病控制程度。通过条件Ｌｏｇｉｓｔｉｃ回归分析方法，分析病例（ｎ＝１０５）、对照（ｎ＝１０５）得以下结果：单因素分析显示糖尿病控制不佳者，患糖尿病视网膜病变的危险性增大，最高血糖值，平均空腹血糖，酮症酸中毒三指标的ＯＲ值分别为２．１５（９５％ＣＩ：１．２８～３．６１），２．１９（９５％ＣＩ：１．５５～３．１０），３．６７（９５％ＣＩ：１．４９～９．０５）。用潜在的混杂因素调整后，平均空腹血糖的作用仍显著；而最高血糖值和酮症酸中毒分别用病程和尿蛋白调整后其作用消失。
The relationship between diabetes blood glucose control and diabetic retinopathy(DR) were examined in a matched case control study.105 cases and their controls were observed by the highest blood glucose,average fasting blood glucose and history of diabetes ketonacidesis.The results were obtained from conditinal logistic regression analysis.The highest blood glucose was greatly risk factor(OR=2 19;95%CI:1 28￣3 16),and then was average fasting blood glucose(OR=2 19,95%CI:1 55￣3 10),3rd was the history of ketonacidosis (OR=3 67;95%CI:1 49￣9 05).After adjustment with other risk factors the average fasting blood glucose was still the risk factor of DR,but the highest blood glucose and history of ketonacidosis were not risk faotors of DR.
出处
《中国慢性病预防与控制》
CAS
1997年第4期159-161,共3页
Chinese Journal of Prevention and Control of Chronic Diseases
