期刊文献+

胰岛素增敏剂在非酒精性脂肪性肝病中的作用 被引量:1

下载PDF
导出
摘要 非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)是一种肝组织学上与酒精性脂肪性肝病相似、但无过量饮酒史的临床病理综合征,以弥漫性肝细胞大泡性脂肪变为主要特征,包括单纯性脂肪肝、脂肪性肝炎(NASH)、肝纤维化和肝硬化.其危险因子包括肥胖、2型糖尿病、高脂血症、手术及药物等。随着肥胖和2型糖尿病在世界范围内广泛流行.与之相关的NAFLD发生率呈显著上升趋势。NAFLD目前已成为西方发达国家最常见的肝病.累及约20%~30%的普通成人,
出处 《内科理论与实践》 2008年第1期23-26,共4页 Journal of Internal Medicine Concepts & Practice
  • 相关文献

参考文献2

二级参考文献12

  • 1XU Ping,ZHANG Xing-guo,LI You-ming,YU Chao-hui,XU Lei,XU Gen-yun.Research on the protection effect of pioglitazone for non-alcoholic fatty liver disease (NAFLD)in rats[J].Journal of Zhejiang University-Science B(Biomedicine & Biotechnology),2006,7(8):627-633. 被引量:17
  • 2Nimer Assy,Masha Grozovski,Ilana Bersudsky,Sergio Szvalb,Osamah Hussein.Effect of insulin-sensitizing agents in combination with ezetimibe, and valsartan in rats with non-alcoholic fatty liver disease[J].World Journal of Gastroenterology,2006,12(27):4369-4376. 被引量:15
  • 3Neuschwander-Tetri BA.Nonalcoholic steatohepatitis and the metabolic syndrome[J].Am J Med Sci,2005,330 (6):326-335. 被引量:1
  • 4Machado M,Cortez-Pinto H.Non-alcoholic fatty liver disease and insulin resistance[J].Eur J Gastroenterol Hepatol,2005,17 (8):823-826. 被引量:1
  • 5Lin HZ,Yang SQ,Chuckaree C,et al.Metformin reverses fatty liver disease in obese,leptin-deficient mice[J].Nat Med,2000,6:998-1003. 被引量:1
  • 6Marchesini G,Brizi M,Bianchi G,et al.Metformin in non-alcoholic steatohepatitis[J].Lancet,2001,358:893-894. 被引量:1
  • 7Nair S,Diehl AM,Wiseman M,et al.Metformin in the treatment of non-alcoholic steatohepatitis:a pilot open label trial[J].Aliment Pharmacol Ther,2004,20:23-28. 被引量:1
  • 8Uygun A,Kadayifci A,Isik AT,et al.Metformin in the treatment of patients with non-alcoholic steatohepatitis[J].Aliment Pharmacol Ther,2004,19:537 -544. 被引量:1
  • 9Hickman IJ,Jonsson JR,Prins JB,et al.Modest weight loss and physical activity in overweight patients with chronic liver disease results in sustained improvements in alanine aminotransferase,fasting insulin,and quality of life[J].Gut,2004,53 (3):413-419. 被引量:1
  • 10Shadid S,Jensen MD.Effect of pioglitazone on biochemical indices of non-alcoholic fatty liver disease in upper body obesity[J].Clin Gastroenterol Hepato1,2003,1 (5):384-387. 被引量:1

共引文献11

同被引文献19

  • 1陆伦根.非酒精性脂肪性肝病的临床特征和自然史[J].国际消化病杂志,2006,26(2):140-141. 被引量:4
  • 2窦艳玲,赵洪川.二甲双胍联合生活方式干预对非酒精性脂肪肝的治疗作用[J].中国实用内科杂志,2007,27(7):523-525. 被引量:5
  • 3Fan JG,Zhu J,Li XJ,et al.Fatty liver and the metabolic syndrome among Shanghai adults[J].J Gastroenterol hepatol,2005,20:1825-1832. 被引量:1
  • 4Yan J,Xie W,Ou WN,et al.Epidemiological survey and risk factor analysis of fatty liver disease of adult residents,Beijing,China[J].J Gastroenterol Hepatol,2013,28:1654-1659. 被引量:1
  • 5Wong VW,Wong GL,Choi PC,et al.Disease progression of non-alcoholic fatty liver disease:a prospective study with paired liver biopsies at 3years[J].Gut,2010,59(7):969-974. 被引量:1
  • 6Pais R,Charlotte F,Fedchuk L,et al.A systematic review of follow-up biopsies reveals disease progression in patients with non-alcoholic fatty liver[J].J Hepatol,2013,59:550-556. 被引量:1
  • 7刘玉兰.从肝肠“对话”谈肝脏疾病[J].中国医学论坛报,2010,36(44):D1. 被引量:1
  • 8Rong X,Li Y,Ebihara M,et al.AngiotensinⅡtype 1receptor-independent beneficial effects of telmisartan on dietary-induced obesity,insulin resistance and fatty liver in mice[J].Diabetologia,2010,53:1727-1731. 被引量:1
  • 9Dunn W,Sanyal AJ,Brunt EM,et al.Modest alcohol consumption is associated with decreased prevalence of steatohepatitis in patients with non-alcoholic fatty liver disease(NAFLD)[J].J hepatol,2012,57:384-391. 被引量:1
  • 10Liangpunsakul S,Chalasani N.What should we recommend to our patients with NAFLD regarding alcohol use?[J].Am J Gastroenterol,2012,107:976-978. 被引量:1

引证文献1

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部