摘要
目的观察IL-6、8、10在缺血性脑卒中急性期的变化及意义。方法采取双抗体夹心ELISA法对20例缺血性脑卒中患者分别在发病后第1、3、7d和15例健康体检者第1d的血清IL-6、IL-8、IL-10进行检测。结果急性缺血性脑卒中患者与正常健康体检者相比,IL-6、IL-8均在发病后第1、3d明显增高(P<0.05);第7d结果相差不大(P>0.05);IL-10在第1、3、7d逐渐增高(P<0.05)。结论白细胞介素的监测可以为早期临床治疗及康复干预提供试验指标,以便控制脑卒中的进展及复发。
Objective To determine the change of plasma interleukin-6,8 , 10 in patients with cerebral infarction. Methods ELISA was applied to determine plasma interleukin-6,8,10 in 20 eases in the first,third and seventh day after stroke and 15 healthy individuals in the first day after stroke. Results Serum interleukin-6,interleukin-8 levels of ease group in the first and the third day after stroke were significantly higher than that of control group （P〈0. 05）, the seventh day after stroke ,ease group was as high as control group（P〉0. 05） ; Serum interleukin-10 levels of ease group at the third day were significantly higher than that of control group （P〈0.05）, the seventh day was highest. Conclusion Surveillance on interleukin can provide experimental indicators for early clinical therapy and rehabilitative intervention, which is good for the control of development and reocurrence.
出处
《中国实用神经疾病杂志》
2008年第2期35-36,共2页
Chinese Journal of Practical Nervous Diseases
