摘要
目的分析腹腔手术后患者医院内下呼吸道感染的常见病原菌及药物敏感情况。方法回顾性分析2002年1月～2007年1月246例腹腔手术后下呼吸道感染患者的痰菌培养结果。结果246例住院患者分离出261株病原菌，其中革兰氏阴性杆菌183株（70．1％），主要为铜绿假单胞菌、流感嗜血杆菌、不动杆菌、副流感嗜血杆菌和克雷伯菌；革兰阳性球菌60株（23．0％），主要为表皮葡萄球菌、肺炎链球菌及金黄色葡萄球；真菌18株（6．8％）。铜绿假单胞菌、不动杆菌、克雷伯菌对美洛培南、舒普深、头孢吡肟敏感；葡萄球菌对万古霉素均敏感；肺炎链球菌对美洛培南、左氟沙星敏感率高，对青霉素大部分耐药。结论下呼吸道感染以革兰氏阴性杆菌感染为主，且常见病原菌耐药性明显，应根据药敏试验规范使用抗生素，减少耐药菌的产生。
Objective To investigate the pathogenic bacteria distribution and susceptibility of nosoeomial lower respiratory tract infection（NLRTI） in patients who underwent abdominal operation. Method From January 2002 to January 2007, 246 NLRTI patients after abdominal operation received sputum or secretion culture. Results A total of 261 clinical isolates were collected, including 183 （70.1% ） strains of gram negative bacilli, 60 （23.0%） strains of gram positive cocci and 18 （6.8%） strains of fungi. The major pathogens in gram negative bacilli were Pseudomonas aeruginosa, Haemophilus influenzae, Aeinetobaeter, Haemophilus parainfluenzae and Klebsiella. The key pathogens in gram positive cocci were Staphylococcus epidermidis, Streptococcus pneumoniae and Staphylococcus aureus. Pseudomonas aeruginosa, Acinetobacter and Klebsiella were susceptible to meropenem, sulperazone and eefepime. In gram positive cocci, Staphylococci were all sus- ceptible to vaneomyein, Streptococcus pneumoniae were highly susceptible to meropenem and levofloxaein, while were highly resistant to penicillin. Conclusions The pathogenic bacteria of NLRTI are main gram negative bacilli with high antibiotics resistance. Antibiotics should be selected according to susceptibility to decrease resistance stains.
出处
《中国现代手术学杂志》
2007年第6期446-448,共3页
Chinese Journal of Modern Operative Surgery
关键词
呼吸道感染
抗菌药
药物敏感性试验
resoiratory tract infection： anti-bacterial agents
parasitic sensitivity tests
