摘要
目的观察罗哌卡因(局麻药)在股神经置管时的镇痛效果。方法60例拟在膝关节镜下行前交叉韧带重建的患者随机分为3组,每组20人。手术后,通过股神经导管,分别间断推注0.2%罗哌卡因(RI组)、持续输注0.2%罗哌卡因(RC组)、0.2%罗哌卡因与0.2μg.mL-1舒芬太尼联合持续输注(RS组)。观察镇痛效果、伍用其他止痛药的情况、并发症。结果RC组和RS组的患者术后许多时间点的镇痛评分均优于RI组(P<0.05);RI组术后使用口服止痛药明显多于RC组和RS组(P<0.05);3组使用哌替啶的次数无明显差异(P>0.1)。3组均无严重并发症。结论持续输注0.2%罗哌卡因对膝关节前交叉韧带重建术后的疼痛有很好的镇痛效果。
Objective To evaluate the effects of pain control achieved with local anesthetic ropivacaine injection or infusion via a femoral nerve catheter in ligament reconstruction patients. Methods Sixty ASA Ⅰ～Ⅱ subjects scheduled to undergo arthroscopically aided anterior ligament reconstruction were randomly allocated to three groups, each group including 20 patients. The first group （RI） received 0.2% ropivacaine 20 mL administered every 6 hours through; patients in the second group （RC） were given a continuous infusion of 0.2% ropivacaine through, at 5 mL · h^-1 ; while the other twenty patients （ group RS） received analgesia with 0.2% ropivacaine and 0.2 μg · mL^-1 sufentanil mixture continuous infusion through a femoral catheter, at 5 mL · h^-1. Results The VAS scores of groups RC and RS were significantly higher than group RI at 8,12,16,24,36 h postoperatively, oral analgesics requirement was still higher in group RI throughout the postoperative observation. The VAS scores were similar between group RC and RS. There was no difference among three groups when compared VAS scores at 0,4,48 h and 60 h after the operation. No obvious adverse effects were found in all groups. Conclusion It was conclude that continuous infusion of 0.2% ropivacaine via femoral nerve catheter can provide excellent postoperative pain control after anterior cruciate ligament reconstruction, addition of sufenltanil can not improve the analgesic effect.
出处
《中国临床药理学杂志》
CAS
CSCD
北大核心
2008年第1期10-13,共4页
The Chinese Journal of Clinical Pharmacology
关键词
罗哌卡因
股神经导管
镇痛
ropivacaine
femoral nerve catheter
analgesia
