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扩大蝶窦入路显微手术切除巨大侵袭性垂体瘤 被引量:2

Microsurgical treatment of giant invasive pituitary adenoma through extemive transsphenoidal approach
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摘要 目的 探讨扩大蝶窦入路显微手术切除巨大侵袭性垂体瘤的方法和治疗效果。方法 本组11例,平均病程4.8年;肿瘤最大径4.0cm-6.3cm;海绵窦均有侵袭,其中单侧侵袭8例,双侧受累3例;4例肿瘤包绕颈内动脉,累及斜坡2例。本组均采用扩大蝶窦入路显微手术切除术切除巨大侵袭性垂体瘤。结果 肿瘤生切除2例,次全切除6例,大部切除3例。结论 扩大经蝶入路。术野显露较大,肿瘤暴露优于传统经蝶入路。充分利用海绵窦静脉丛已大部分乃至完全闭塞的解剖特点。切开海绵窦。最大限度的切除肿瘤。 Objective To explore the method and therapeutic effect of microsurgical treatment of giant invasive pituitary adenoma through extensive transsphenoidal approach. Methods The clinical data of 11 patients with giant invasive pituitary adenoma treated by extensive transsphenoidal approach were analyzed retrospectively. In all of the 11 patients, pituitary adenoma were larger than 4 em in diameter, invading the eavemons sinus, including 8 unilateral invasion to the eavemons sinus, 3 bilateral invasion 4 wrapped internal carotid artery , 2 including elivus. Results Of 11 eases, tumors of 2 were totally reseeted and 6 subtotally. Conclusion Extensive transsphenoidal approach has prominent benefit on microsurgical treatment of giant invasive pituitary adenoma by amply exposing operational area ,and split the occlusive eavemons sinus .
出处 《内分泌外科杂志》 2008年第1期18-19,共2页
关键词 巨大侵袭性垂体瘤 扩大蝶窦入路 Giant invasive pituitary adenoma Extensive transsphenoidal approach
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  • 1张荣伟,杨辉,袁绍纪,刘子生,卢培刚,孙希炎,吕学明.扩大经蝶入路显微手术治疗海绵窦侵袭性垂体瘤[J].中国微侵袭神经外科杂志,2006,11(6):269-270. 被引量:18
  • 2Knosp E, Steiner E, Kitz K, et al. Pituitary adenomas with invasion of the cavernous sinus space : a magnetic resonance imaging classification compared with surgical, findings [ J ]. Neurosurgery, 1993, 33(4) :610 -618. 被引量:1
  • 3Schwartz TH, Anand VK. The endoscopic endonasal transsphenoidal approach to the suprasellar cistern [ J ]. Clinical Neurosurgery, 2007,54:226 - 235. 被引量:1
  • 4de Divitiis E, Cappabianea P, Cavallo LM. endoscopic transsphenoidal approach : adaptability of the procedure to different sellar lesions[ J]. Neurosurgery, 2002,51 (3) : 699 -707. 被引量:1
  • 5Kitano M, Taneda M. Extended transsphenoidal approach with submucosal posterior ethmoidectomy for parasellar tumors [ J ]. J Neurosurg ,2001,94 ( 6 ) :999 - 1004. 被引量:1
  • 6Amin K, Carl HS, Arian M, et al. Expanded endonasal approach : the rostrocaudal axis. Part Ⅰ . Crista galli to the sella turcica[ J]. Neurosurg Focus, 2005,19( 1 ) : E3. 被引量:1
  • 7Kitano M, Taneda M, Shimono T, et al. Extended transsphenoidal approach for surgical management of pituitary adenomas invading the cavernous sinus [ J ]. J Neurosurg, 2008,108 ( 1 ) : 26 - 36. 被引量:1
  • 8Couldwell WT, Weiss MH, Rabb C, et al. Variations on the standard transsphenoidal approach to the sellar region, with emphasis on the extended approaches and parasellar approaches : surgical experience in 105 cases[ J]. Neurosurgery, 2004,55 (3) : 539 - 550. 被引量:1
  • 9刘力强,方艳伟,耿少梅,焦保华,马树成,郭二坤,卢圣奎,张广宇.翼点联合额下入路显微手术切除巨大侵袭性垂体腺瘤19例报告[J].中国医师进修杂志,2013,36(8):43-45. 被引量:1
  • 10刘希光,李爱民,李宁,陈军,施辉,王富元.经颅切除巨大侵袭型垂体腺瘤手术入路的选择与显微手术策略[J].脑与神经疾病杂志,2013,21(4):293-297. 被引量:6

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