摘要
目的调查深圳市首例人感染高致病性禽流感病例流行病学,探索无动物禽流感暴露史情况下的可能感染源,为进一步认识与防治禽流感提供科学依据。方法用描述流行病学、荧光定量PCR、ELISA、RT-PCR和应急监测等方法进行调查、诊断。结果发现深圳市首例人感染高致病性禽流感病毒(H5N1)确诊病例,无明确病死禽接触史,密切接触者中无不明原因肺炎病例,未发现人-人传播证据。结论深圳市首例人感染高致病性禽流感病例属感染个案,非人传人的病例,感染来源可能与农贸市场环境有关。
OBJECTIVE To analyze possible source of infection under the condition of no exposure to sick or dead poultry and provide scientific evidence for further prevention and control of avian influenza by epidemiologic investigation of the first case infected with highly pathogenic avian influenza virus （H5N1） in Shenzhen. METHODS Descriptive epidemiology, emergency surveillance,ELISA and real-time PCR （RT-PCR） were used for analysis and diagnosis concerning the first H5N1 response. RESULTS The first case infected with H5N1 in Shenzhen was confirmed. But history of exposure to infected poultry, pneumonia of unknown etiology from close contacts and evidence of human-to-human transmission were not found. CONCLUSIONS The first H5N1 patient in Shenzhen is not a case induced by human-to-human transmission and the infection source might be from the farmers＇ market.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2008年第1期41-44,共4页
Chinese Journal of Nosocomiology
