摘要
目的:探讨老年原发性高血压(essential hypertention,EH)患者血糖水平与血脂、胰岛素水平的关系。方法:比较EH组与对照组及EH按血糖水平分组后与对照组的总胆固醇(total cholesterol,TC)、三酰甘油(triglyceride,TG)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)和空腹血浆胰岛素(fasting plasma insulin,FINS)的水平。结果:EH组患者血脂成分及胰岛素水平均较对照组有显著性差异(P<0.01,P<0.05)。EH组与对照组相比,EH组的TC、TG、LDL-C、FINS显著升高(P<0.01,P<0.05),HDL-C显著降低(P<0.05)。结论:EH患者胰岛素抵抗(insulin-resistance,IR)水平增加是血脂异常的原因之一,血脂异常的程度随糖尿病病程的进展而加重。
Objective： Evaluating the effects of plasma glucose level in lipid phenotype and levels of plasma insulin in elderly hypertension.Methods： Comparing the TC,TG,HDL-C,LDL-C,FINS and glucose between the hypertensive group and control group,the subgroup and the control group.Results： Compared with the control group, the lipid phenotype and insulin levels were abnormal greatly in hypertensives （P〈0.01,P〈0.05）,in subgroups,the level of TC,TG,LDL-C and FINS increased and the HDL-C level decreased than those of control group （P〈0.01,P〈0.05）. Conclusion： The increasing of insulin-resis- tance may be one of the causes of dyslipidemia in EH patients and the dyslipidemia phenotype related with the increased type 2 diabetes mellitus.
出处
《中国医药导报》
CAS
2008年第1期39-40,共2页
China Medical Herald
