摘要
目的探讨血清中胆红素及血脂水平与冠心病之间的关系。方法42例病人,经冠脉造影证实为冠心病者23例,冠脉造影正常的19例。另外,诊断明确的急性心肌梗死病人15例。取血测定血清胆红素及血脂,比较冠心病病人和对照组之间有无变化。结果冠心病组病人LDL-C较对照组明显增高而DBIL明显降低,两组相比具有显著差异性(P<0.05)。虽然冠心病病人TC、TG较对照组增高,而HDL及TBIL较对照组降低,但两组相没有显著差异性。急性冠脉综合症病人与稳定性心绞痛病人相比,虽然LDL-C较高,TBIL较低,但两组相比没有差异性,而DBIL较低,两组相比具有显著差异性(P<0.05)。结论血清中胆红素和LDL-C参与了冠心病的发生,血清中胆红素可能参与了急性冠脉综合症的发生。
Objective To investigate the relationship between serum bilirubin as well as lipid and coronary heart disease.Method 42 paients with coronary angiography and 15 patients with acute myocardial infarction were enrolled in this study. Serum bilirubin and lipid were assayed and compared their changes in different groups. Results Serum LDL-C levels increased significantly in patients with coronary heart disease and serum bilirubin decreased significantly.Changes of other lipid levels and TBIL did not reach significantly, Serum levels of DBIL in patients with acute coronary syndrome increased significantly compared with stable angina pectoris. And other parameters showed no significance.Conclusion Changes of LDL-C and bilirubin were related to patients with coronary heart disease.Changes of bilirubin were only related to patients with acute coronary syndrome.
出处
《中国血液流变学杂志》
CAS
2007年第4期578-579,608,共3页
Chinese Journal of Hemorheology
关键词
冠心病
胆红素
血脂
coronary heart disease
bjlirubin
lipid
