阿片肽及阿片受体在心血管系统作用及机制的研究进展
被引量:1
摘要
近年来,随着对阿片肽及阿片受体研究的不断深入,人们发现阿片肽及阿片受体与心血管系统的关联日益加深,心肌细胞膜和血管壁上存在大量的阿片受体,其在心脏疾病的发生、发展中具有重要的意义,本文对阿片肽及阿片受体以及其发挥对心血管系统调控作用的途径进行综述。
出处
《辽宁医学院学报》
CAS
2007年第5期81-83,共3页
Journal of Liaoning Medical University (LNMU) Bimonthly
参考文献13
-
1[1]Martin WR The effects of morphine and nalorphine-like drugs in the non dependent and morphine-dependent chronic spinal dog[J].J Phannacol Exp Ther,1976,197:517. 被引量:1
-
2[2]Richard JK.Molecular biology and pharmacology of cloned opioid recetors[J].FASEB,1995,9:516. 被引量:1
-
3[3]Kieffer BL,The δ-opioid receptor isolation of a cDNA by expression cloning and pharmacological charaterization[J].Proc Natl Acad Sci USA,1992,89:12048. 被引量:1
-
4[4]Chen Y,Mestek A,Liu J,et al.Molecular clorning and funcrional expression of a μ-opioid receptor from rat brain[J].Mol Pharmacol,1993,44:8. 被引量:1
-
5[5]Minami M,Toya T,Katao Y,et al.Cloning and expression of a cDNA for the ratκ-opioid receptor[J].FEBS Lett,1993,329:291. 被引量:1
-
6[6]Sheng JZ,Wong NS,Wang HX,et al.Pertussistoxin,but not tyrosine kinase inhibitor,abolishes effects of U50488H on[Ca2+]I in myocytes[J].Am J Physiol,1997,272:560. 被引量:1
-
7[7]Yu XC,Li HY,Wang HX,et al.U50488H inhibits effects of norepinephrine in rat cardiomyocytes-cross-talk between κopioid and β-adrenoceptors[J].J Mol Cell Cardiol,1998,30:405. 被引量:1
-
8[8]Yu XC,Li HY,Wang HX,et al.U50488H inhibits effects of norepinephrine in rat cardiomyocytes-cross-talk between κopioid and β-adrenoceptors[J].J Mol Cell Cardiol,1999,31:1809. 被引量:1
-
9[9]Sheng JZ,Wong NS,Tai KK,et al.Lithium attenuates the effects of dynorphin A(1-13)on inositol1,4,5-trisphophate and intracellular Ca2+in rat ventricular[J].Life Sci,1996.59:2181. 被引量:1
-
10[10]Schltz JJ,Hsu AK,Gross GJ.Ischem ic Preconditioning and morphine induced cardio protection involve the delta-opioid receptor in the intact rat heart[J].J Mol Cell Cardiol,1997,29(8):2187-2195. 被引量:1
二级参考文献8
-
1[1]Wang Y, Takashi E, Xu M, Ayub A, Ashraf M. Downregulation of protein kinase C inhibits activation of mitochondrial K (ATP) channels by diazoxide [J]. Circulation, 2001; 104(1): 85-90. 被引量:1
-
2[2]Yao Z, McPherson BC, Liu H, Shao Z, Li C, Qin Y, Vanden Hoek TL, Becker LB, Schumacker PT. Signal transduction of flumazenil-induced preconditioning in myocytes [J]. Am J Physiol Heart Circ Physiol, 2001; 280(3): H1249-255. 被引量:1
-
3[3]Wang S, Cone J, Liu Y. Dual roles of mitochondrial K (ATP) channels in diazoxide-mediated protection in isolated rabbit hearts [J]. Am J Physiol Heart Circ Physiol, 2001; 280(1): H246-255. 被引量:1
-
4[4]Carroll R, Yellon DM. Delayed cardioprotection in a human cardiomyocyte-derived cell line: The role of adenosine, p38MAP kinase and mitochondrial KATP [J]. Basic Res Cardiol, 2000; 95(3): 243-249. 被引量:1
-
5[5]Tonkovic-Capin M, Gross GJ, Bosnjak ZJ, Tweddell JS, Fitzpatrick CM, Baker JE. Delayed cardioprotection by isoflurane: Role of K (ATP) channels [J]. Am J Physiol Heart Circ Physiol, 2002; 283(1): H61-68. 被引量:1
-
6[6]Patel HH, Hsu AK, Peart JN, Gross GJ. Sarcolemmal K (ATP) channel triggers opioid-induced delayed cardioprotection in the rat [J]. Circ Res, 2002; 91(3): 186-188. 被引量:1
-
7[7]Ohnuma Y, Miura T, Miki T, Tanno M, Kuno A, Tsuchida A, Shimamoto K. Opening of mitochondrial K (ATP) channel occurs downstream of PKC-epsilon activation in the mechanism of precondition [J]. Am J Physiol Heart Circ Physiol, 2002; 283(1): H440-447. 被引量:1
-
8[8]Yue Y, Qin Q, Cohen MV, Downey JM, Critz SD. The relative order of mito K (ATP) channels, free radicals and p38 MAPK in preconditioning's protective pathway in rat heart [J]. Cardiovasc Res, 2002; 55(3): 681-689. 被引量:1
共引文献7
-
1刘睿,张岫美.阿片样物质参与心血管系统调控[J].中国药理学通报,2005,21(4):497-500. 被引量:6
-
2昝香怡,李培杰,张正义,汤晓琴,赵建洪,曹文.阿片受体拮抗剂对大鼠心肌缺血/再灌注损伤的保护效应[J].中国危重病急救医学,2007,19(11):693-694. 被引量:9
-
3付志强,方文倩,闻国春,吕国义,邓迺封.线粒体ATP敏感性钾通道在利多卡因预先给药减轻大鼠离体心脏缺血再灌注损伤中的作用[J].中华麻醉学杂志,2010,30(12):1489-1492. 被引量:3
-
4张治国,齐颖.ATP敏感性钾通道抗心肌缺血再灌注损伤机制研究进展[J].包头医学院学报,2011,27(5):116-118. 被引量:3
-
5王倩梅,贾敏,冯娜,张淑苗,李娟,樊荣,王跃民,裴建明.κ-阿片受体激动剂U50488H的季胺化改造[J].心脏杂志,2013,25(2):185-189.
-
6朱小兵,刘志群,吴论,刘志龙,卫毅,石翊飒,张喜洋.mito-KATP通道在利多卡因预先给药减轻大鼠肾脏缺血再灌注损伤中的作用[J].中华麻醉学杂志,2013,33(11):1322-1325. 被引量:2
-
7朱小兵,吴论,刘志群,王根宝.mito-KATP通道在利多卡因减轻肾缺血再灌注心肌损伤的作用[J].中国热带医学,2015,15(10):1169-1171.
同被引文献16
-
1Zadina JE,Hackler L,Ge LJ,et al.A potent and selective endogenous agonist for theμ-opioid receptor[J].Nature,1997,386(6624):499-502. 被引量:1
-
2Hackler L,Zadina JE,Ge LJ,et al,Isolation of relatively large amounts of endomorphin-1 and endomorphin-2 from human brain cortex[J].Peptides,1997,18(10):1635-1639. 被引量:1
-
3Champion HC,Zadina JE,Kastin AJ,et al.The endogenousμ-opioid agonists endomorphin 1 and 2 have novel hypotensive activity in the rabbit[J].Biochm Biophys Res Commun,1997,235(3):567-570. 被引量:1
-
4Champion HC,Zadina JE,Kastin AJ,et al.Endomorphin 1 and 2have vasodepressor activity in the anesthetized mouse[J].Peptides,1998,19(5):925-929. 被引量:1
-
5Champion HC,Bivalacqua TJ,Lambert DG,et al.Endomorphin1and 2,the endogenous mu-opioid agonists,produce biphasic changes in systemic arterial pressure in the cat[J].Life Sci,1998,63(9):PL131-136. 被引量:1
-
6Kwok EH,Dun NJ.Endomorphins decrease heart rate and blood pressure possibly by activating vagal afferents in anesthetized rats[J].Brain Res,1998,803(1-2):204-207. 被引量:1
-
7Czapla MA,Champion HC,Zadina JE,et al.Endomorphin l and 2,endogenous mu-opioid agonists,decrease systemic arterial pressure in the rat[J].Life Sci,1998,62(13):PL175-179. 被引量:1
-
8QI Yuanming,YANG Dingjian,DUAN Xin,et al.Endomorphins inhibit contractile responses of rat thoracic aorta rings induced by phenylephrine and angiotensinⅡin vitro[J].Acta Pharmacol Sin,2002,23(1):40-44. 被引量:1
-
9Champion HC,Bivalacqua TJ,Zadina JE,et al.Vasodilator response to the endomorphin peptides,but not nociceptin/OFQ are mediated by nitric oxide release[J].Ann NYA cad Sci,1999,897:165-172. 被引量:1
-
10Brady AJ,Warren JB,Poole-Wilson PA,et al.Nitric oxide attenuates cardiac myocyte contraction[J].Am J Physiol,1993,265(1 pt2):H176-182. 被引量:1
-
1白宇飞,王红娟,马欣.碘对血管平滑肌作用的实验研究进展[J].国外医学(医学地理分册),2004,25(3):97-100. 被引量:1
-
2陶利,李禾.大豆异黄酮的药理作用[J].解放军药学学报,2011,27(4):360-362. 被引量:11
-
3钱一鑫,何珺,李洪庆,康冀川.大豆苷元药剂学研究进展[J].中草药,2008,39(9):1429-1434. 被引量:8
-
4王宁,周远大,杨辉,何海霞.吐温-80对大鼠心血管系统作用的影响[J].中国药房,2004,15(5):273-275. 被引量:16
-
5胡欣春 ,徐建军 .神经肽Y的心血管系统作用[J].江西医药,2004,39(1):59-63.
-
6钟伟,李家富.Urocortin及其心血管系统作用的研究进展[J].山东医药,2010,50(35):115-116. 被引量:2
-
7夏宗勤.争取受体研究取得更快更大的发展[J].核技术,1999,22(11):641-641.
-
8周金彩,王疑芳.银杏叶提取物对心血管系统的作用[J].现代医药卫生,2010,26(8):1178-1179. 被引量:4
-
9陆迪菲,马晓伟,郭晓蕙.二肽基肽酶-4心血管系统作用的研究进展[J].中国糖尿病杂志,2016,24(11):1049-1051. 被引量:5
-
10Rochelle Chaiken.瑞易宁受体研究及其临床意义[J].国外医学(内分泌学分册),2003,23(4):232-233. 被引量:2