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Liver synthetic function in predicting the prognosis of pregnancy complicating fulminant hepatitis 被引量:6

Liver synthetic function in predicting the prognosis of pregnancy complicating fulminant hepatitis
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摘要 Pregnancy complicating fulminant hepatitis is characterized by rapid progress, complicated clinical symptoms, and association with blood coagulation dysfunction, hepatic encephalopathy, hepatorenal syndrome, toxic enteroparalysis and infection. Late pregnancy complicating fulminant hepatitis, which has a high fatality rate, is one of the maior causes of death of gravida and puerperant in China. Searching for exact objective indexes and correct judgement of the prognosis is extremely important to clinical work. The indexes of liver function mainly include (1) indexes for the damage of hepatic cells and its degree such as alanine transaminase (ALT), etc; (2) indexes for the synthesis function of hepatic cells such as albumin (ALB), total cholesterol (CHOL), prothrombin time (PT), prothrombin activity (PTA), etc; (3) indexes for the function of liver excretion, metabolism and detoxication such as total bilirubin (TBIL), total bile acid (TBA), blood ammonia (NH3), etc. Pregnancy complicating fulminant hepatitis is characterized by rapid progress, complicated clinical symptoms, and association with blood coagulation dysfunction, hepatic encephalopathy, hepatorenal syndrome, toxic enteroparalysis and infection. Late pregnancy complicating fulminant hepatitis, which has a high fatality rate, is one of the maior causes of death of gravida and puerperant in China. Searching for exact objective indexes and correct judgement of the prognosis is extremely important to clinical work. The indexes of liver function mainly include (1) indexes for the damage of hepatic cells and its degree such as alanine transaminase (ALT), etc; (2) indexes for the synthesis function of hepatic cells such as albumin (ALB), total cholesterol (CHOL), prothrombin time (PT), prothrombin activity (PTA), etc; (3) indexes for the function of liver excretion, metabolism and detoxication such as total bilirubin (TBIL), total bile acid (TBA), blood ammonia (NH3), etc.
出处 《Chinese Medical Journal》 SCIE CAS CSCD 2007年第24期2311-2313,共3页 中华医学杂志(英文版)
基金 This study was supported by grants from the Technological Project of Guangdong Province(No.2005B340201006) the Bureau of Traditional Chinese Medicine and Drugs of Guangdong Province(No.1060166)
关键词 PREGNANCY fulminant hepatitis liver function PROGNOSIS pregnancy fulminant hepatitis liver function prognosis
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