摘要
采用干血滴纸片法测新生儿出生后72小时足跟血的促甲状腺素（TSH）作为筛选指标。共筛选新生儿51582名，超出筛查均值的异常者随访复查血清三碘甲状腺原氨酸（T3）、甲状腺素（T4）及TSH含量，查出先天性甲低患儿10名，提示检测足跟血（血片）中的TSH含量作为筛查指标是可靠的。并对筛选的目的、意义、方法及治疗等，进行了探讨。
51582 newborns were screened from january 1993 to june 1996 for hypothyroidism and 10 patients were identibied. 72 hours after birth were adopted for diagnosis of hypothyroidism. RIA and IRMA method was used for their determination. If TSH level is over cutoff va1ue, T3 T4 TSH level in vein blood should be further measuremented. The result showed that TSH screening method in heel blood as screen standed is reliable. Aim significance and method of screen were explored. Detected infants with hypothyroidism were treated with thyroid extract tablets. Physical and mental development of 10 patients showed no difference from normal children of the same age.
出处
《中国优生与遗传杂志》
1997年第4期46-47,44,共3页
Chinese Journal of Birth Health & Heredity
