摘要
目的探讨脑电双频指数(BIS)指导吸入异氟醚对全麻病人恢复和麻醉用药的影响。方法在全麻下择期行腹部手术患者40例,ASAⅠ～Ⅱ级,随机分为对照组和BIS组,每组20例。BIS组:在BIS监测下指导术中异氟醚的吸入浓度,维持BIS在50～60。对照组:在平均动脉压比诱导前升高25%、心率>100次/min时增加异氟醚的吸入浓度。关好腹膜后,BIS组根据BIS维持在60～70减少异氟醚的吸入浓度,对照组麻醉医生根据经验减少异氟醚的吸入浓度。记录异氟醚的用量和芬太尼用量;诱导后至拔管记录每5分钟BIS、挥发罐设定浓度和呼气末稳态(ETiso);麻醉诱导前、手术结束、拔管后的BIS值;手术结束时的ETiso值;手术时间,拔管时间。结果与对照组相比,异氟醚用量减少了30%,芬太尼的用量无明显差别;BIS组麻醉期间的BIS高于对照组,在麻醉期间和手术结束时ETiso低于对照组,比对照组拔管时间缩短。结论BIS指导异氟醚吸入麻醉能加快全麻手术病人麻醉早期恢复,并减少异氟醚的用量。
Objective To investigate the effect of bispectral index （ BIS ） monitoring during isoflurance anesthesia on anesthesia recovery period and isoflurane requirement. Methods Forty patients （ ASA Ⅰ or Ⅱ ） underwent elective intra-abdominal surgery were randomly divided into two groups （ n = 20 ） ： BIS group and control group. In the BIS group,isoflurance was inhaled to keep BIS values between 50 to 60 dur ing operation. In the control group, If MAP was increased by 25% of the baseline value or HR 〉 100/min isoflurance concentration was increased. Before the end of operation, the BIS value was increased to 60 to 70 in B1S group. In control group the depth of anesthesia was reduced based on the clinical experience of the anesthesiologist. The related paramtem were recorded and compared between the two groups druing anesthesia. Results The total amount of consumed isoflurance was 30% lower in BIS group than that in control group. There was no significant difference in fentanyl consumption and operation time between the two groups. The average BIS values were higher;the end tidal isoflurance（ ETiso） was lower;extubation time was shorter in B1S group than that in control group. Conclusions Titration of isoflurance using BIS monitoring can reduce the dose of isoflurance during operation and improve early recovery from anesthesia.
出处
《中国厂矿医学》
2007年第6期581-582,共2页
Chinese Medicine of Factory and Mine
