摘要
约1/3的先天性白内障与遗传有关。随着分子生物学技术的发展,近年来愈来愈多地发现Cx50缝隙连接蛋白与先天性白内障有关,其发病机制还不是很明确。本文通过对与缝隙连接蛋白Cx50相关的先天性白内障分子基础的研究做一综述,以期对缝隙连接蛋白分子结构、作用、致病机制有更深的了解。
Nearly one third of the congenital cataract cases are inherited . With the development of molecular biology, more and more research shows that Cx50 is related to congenital cataract without definite pathogenesis. To enrich and deepen our understandings of molecular structure, function and pathogenesis of connexin , this review summarizes the molecular basis of congenital cataract associated with Cx50.
出处
《国际眼科杂志》
CAS
2007年第6期1658-1661,共4页
International Eye Science
