摘要
目的:探讨胎盘型谷光甘肽S-转移酶(GSTP1)在不同病变前列腺组织中的表达情况及意义。方法:将良性增生组(BPH)和前列腺癌组(PC)样本,应用免疫组织化学SP法检测GSTP1的表达。结果:GSTP1在BPH的组织中表达显著高于PC组织(P<0.01)。结论:GSTP1与前列腺癌发生、发展密切相关。
Objective ：To explore the expression of glutathione S--transferase P1 （GSTP1）in the tissues of different types of prostatic diseases. Methods. We used immunohlstochemistry to detect GSTP1 expression in the benign prostate hyperplasia（BPH）and prostate carcinoma（PC） samples. Results：GSTP1 in BPH tissue was significantly higher than that in PC tissue, with significant difference （P 〈 0.01） . Conclusion：The GSTP1 expression may be closely correlated with the genesis and progress of prostate carcinoma.
出处
《黑龙江医药科学》
2007年第6期15-16,共2页
Heilongjiang Medicine and Pharmacy
基金
黑龙江省教育厅项目:11521274
关键词
前列腺癌
前列腺增生
谷胱甘肽-S-转移酶P1
prostate carcinoma
benign prostate hyperpla--sia
glutathione S--transferase P1
