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小剂量多巴酚丁胺-异舒吉超声心动图负荷试验检测冠心病人存活心肌 被引量:1

Low-dose dobutamine-isoket stress echocardiography detecting hibernating myocardium in patients with coronary artery disease
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摘要 目的:探讨异舒吉(isoket)对小剂量多巴酚丁胺超声负荷试验(LDDSE)的影响。方法:将39例研究对象依据冠脉造影的结果分为3组:对照组(CON)12例、冠心病1组(CAD1)15例和冠心病2组(CAD2)12例,其中CAD2行LDDSE+isoket,其余两组行LDDSE,以冠脉介入性治疗(PCI)后室壁运动改善的结果作为评价LDDSE的标准。结果:isoket可以明显增加心率,降低收缩压,但对舒张压影响轻微。CAD2组存活心肌的检出率和敏感性明显高于CAD1组。结论:isoket可提高LDDSE存活心肌检出率。 Objective: To observe the effect of isoket on low-dose dobutamine stress echocardiography(LDDSE).Methods: 39 patients were divided into three groups according to the results of quantitative coronary angiography (QCA):the control group (CON) including 12 patiens,the coronary artery disease group 1 (CAD1) including 15 patients,and the coronary artery disease group 2 (CAD2) including 12 patients. Among the three group,the LDDSE+isoket was done in CAD2,while the LDDSE was done in the other two groups. The improvement of segments of left ventricular after percutaneous transluminal intervention(PCI) was looked as the standard evaluating LDDSE.Results: Isoket could increase heart rate and decrease SBP, but could hardly affect DBP. The rate detecting viable myocardium and sensitivity were improved significantly in group CAD2. Conclusion: LDDSE combined with isoket was benefit for detecting viable myocardium.
机构地区 徐州市第三医院
出处 《中国医药导报》 CAS 2007年第12X期76-77,共2页 China Medical Herald
关键词 小剂量 多巴酚丁胺负荷超声心动图 异舒吉 存活心肌 Low-dose Dobutamine stress echocardiography Isoket Viable myocardium
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参考文献4

  • 1Segar DS,Brown SE.Dobutamine stress echocardiography:correlation with coronary lesion severity as determined by quantitative angiography[].Journal of the American College of Cardiology.1992 被引量:1
  • 2Kaul S.Dobutamine echocardiography for detecting myocardial viability after reperfusion:experimental and clinical observations[].European Heart Journal.1995 被引量:1
  • 3Fallen EL,Nahmias C,Scheffel A,et al.Redistributim of myocardial blood flow with topical Nitroglycerin in patients with coronary artery disease[].Circulation.1995 被引量:1
  • 4Ma LJ,Chen LL,Gillam L,et al.Nitroglycerin enhances the ability of dobutamine stress echocardiography to detect hibernating myocardium[].Circulation.1997 被引量:1

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