摘要
目的:了解医院住院患者抗菌药物的使用情况,为临床合理用药提供参考。方法:采用回顾性调查方法,随机分别抽取医院某日内门诊普通处方100份和9个月内出院患者病历5862份,并调取住院药房抗菌药物的消耗数量,考察门诊患者合理用药的处方指标、住院患者不合理用药表现及抗菌药物用药频度(DDDs)的排序情况。结果:医院门诊患者的处方用药基本合理,但住院患者围手术期抗菌药物的预防性使用存在诸多问题;在DDDs排序中替硝唑用量较高,居前5位的药物以序为替硝唑注射液、头孢哌酮钠/舒巴坦钠针、阿莫西林/克拉维酸钾针、青霉素针、加替沙星针,基本处于动稳状态。结论:医院抗菌药物使用基本合理,但也存在不合理现象,需要采取积极的干预措施,减少抗菌药物滥用。
Objective： To understand the application status ofantibacterials among patients in hospital so as to provide the reference of rational administration of drug. Methods： A retrospective study was conducted, in which 100 outpatients＇ prescriptions in one day and 5862 case histories of discharged patients in 9 months in hospital were randomly selected. The consumption volume of antibacterial drug was stated, and the prescription indicators of the outpatient for rational drug use were investigated, and inpatients＇ non rational use of drugs and DDDs sequence of antibacterials used were manifestated. Results： Outpatients＇ drug use in hospital was basically reasonable but there are several problems involving in perioperative preventive medication of antibacterials.In the rank of DDDs, the dosage of tinidazole is t h e highe s t. The top five medicines are tinidazole injection, cefoperazone sodium and sulbactam sodium, amoxicillin sodium and clavulanate potassium, penicillin and gatifloxacin and basically they are in a state of dynamic stability. Conclusion： The prescription of antibacterial drugs in hospital is reasonable on the whole, except for some unreasonable phenomena, so the active and efficient intervention measures should be taken to reduce the abuse of antibacterials.
出处
《抗感染药学》
2007年第4期190-193,共4页
Anti-infection Pharmacy
