摘要
目的:提高对恶性腹膜间皮瘤的诊断和治疗水平。方法:对我院40年来收治的22例恶性腹膜间皮瘤患者的临床资料结合相关文献进行回顾性分析。结果:22例收治经病理证实的患者,男性9例,女性13例,年龄18～72岁,13例行减瘤手术+腹腔或/和全身化疗,1例行手术减瘤+腹部放疗;4例行剖腹探查+腹腔及全身化疗;1例未手术,仅行腹腔+全身化疗;3例未手术,仅行全身化疗。经治疗后随访中位生存期18.5月,3例存活超过5年。结论:恶性腹膜间皮瘤诊断困难,易误诊,预后差,主要依靠剖腹探查、腹水细胞学、B超引导穿刺活检、腹腔镜活检等方法,治疗主要以手术切除减瘤术结合全身化疗的综合治疗为主要手段。
Objective： To summarize the experience of diagnosis and management of malignant peritoneal mesothelioma. Methods： We reviewed the clinical data from 22 patients with malignant peritoneal mesothelioma who were admitted in our hospital in the past 40 years. Results： All of the diagnosis were proved pathologically, 9 males and 13 females, with a median age of 49,（range 18-72 years）. Thirteen cases underwent eytoreduetive surgery and intraperitoneal and/or systematic chemotherapy, 1 ease received eytoreduetive surgery and abdominal regional radiotherapy, 4 eases had laparotnmy exploration and intraperitoneal and/or systematic ehemntherapy, 1 ease reeeived intraperitoneal and systematic ehemotherapy without surgery, and 3 cases only received systematic chemotherapy. The median survival time was 18.5 months, and there were 3 patients who survived over 5 years. Conclusion： The diagnosis of malignant peritoneal mesothelioma is diffieuh, and its prognosis is poor. Diagnostic methods include laparotomy exploration, ascites cytological examination, fine needle biopsy guided by B-US, and biopsy by laparoscope. Surgical cytoreduction combined with chemotherapy is the main management.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2007年第23期1365-1367,共3页
Chinese Journal of Clinical Oncology
关键词
恶性腹膜间皮瘤
诊断
治疗
Malignant peritoneal mesothelioma Diagnosis Therapy
