摘要
综述了骨组织工程支架材料的设计与制造的发展现状。骨缺损的修复一直是骨组织工程不断深入研究的重要课题之一,然而迄今为止临床上对创伤、感染和肿瘤切除后所造成的大范围的骨缺损仍没有得到有效地解决。骨组织工程研究的重点是寻求用来作为细胞移植与引导新骨生长的细胞支架,作为细胞外基质的替代物。
It is now generally recognized that repairing of defect bones is one of the major issues in bone tissue engineering research. However, nowadays massive bone defect because of injury, infection or tumor removal has not been effectively solved in clinic. One of the key issues in bone tissue engineering is finding suitable biodegradable materials substitutes and scaffolds for seeding cells and guiding the subsequent growth of bone. The design and fabrication of bone tissue engineering scaffolds are overviewed as well as the development of the scaffold materials.
出处
《医疗卫生装备》
CAS
2007年第12期29-31,共3页
Chinese Medical Equipment Journal
关键词
骨缺损
组织工程支架
支架制备
bone defect
tissue engineering scaffolds
scaffolds fabrication
